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Collection  10 March 2022

Journal Top 100

This collection highlights our most downloaded* research papers published in 2021. Featuring authors from around the world, these papers highlight valuable research from an international community.

*Data obtained from SN Insights which is based on Digital Science’s Dimensions.

image of abstract blue network

A well-trained artificial neural network for predicting the rheological behavior of MWCNT–Al 2 O 3 (30–70%)/oil SAE40 hybrid nanofluid

  • Mohammad Hemmat Esfe
  • S. Ali Eftekhari
  • Davood Toghraie

research papers 2021

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

  • Sandra Lopez-Leon
  • Talia Wegman-Ostrosky
  • Sonia Villapol

research papers 2021

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers

  • Joseph M. Rootman
  • Pamela Kryskow

research papers 2021

Detection of persistent SARS-CoV-2 IgG antibodies in oral mucosal fluid and upper respiratory tract specimens following COVID-19 mRNA vaccination

  • Aubree Mades
  • Prithivi Chellamathu
  • Albina Ibrayeva

Causes of death and comorbidities in hospitalized patients with COVID-19

  • Sefer Elezkurtaj
  • Selina Greuel
  • David Horst

research papers 2021

5G as a wireless power grid

  • Jimmy G. D. Hester
  • Manos M. Tentzeris

research papers 2021

Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection

  • Alvin Kuo Jing Teo
  • Yukti Choudhury
  • Li Yang Hsu

research papers 2021

Mathematical modelling of SARS-CoV-2 variant outbreaks reveals their probability of extinction

  • Henrik Schiøler
  • Torben Knudsen
  • Martin Bøgsted

research papers 2021

Mapping the NFT revolution: market trends, trade networks, and visual features

  • Matthieu Nadini
  • Laura Alessandretti
  • Andrea Baronchelli

research papers 2021

Overcooling of offices reveals gender inequity in thermal comfort

  • Thomas Parkinson
  • Stefano Schiavon
  • Gail Brager

research papers 2021

Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit

  • Ayham Daher
  • Paul Balfanz
  • Christian G. Cornelissen

research papers 2021

Positive effects of COVID-19 lockdown on air quality of industrial cities (Ankleshwar and Vapi) of Western India

  • Ritwik Nigam
  • Kanvi Pandya
  • Mahender Kotha

Proportion of people identified as transgender and non-binary gender in Brazil

  • Giancarlo Spizzirri
  • Raí Eufrásio
  • Carmita Helena Najjar Abdo

research papers 2021

Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

  • Swapnil Mahajan
  • Vasumathi Kode
  • Amitabha Chaudhuri

research papers 2021

Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing

  • L. S. Kaertner
  • M. B. Steinborn
  • R. L. Carhart-Harris

research papers 2021

Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial

  • Jae H. Kang
  • Chirag M. Vyas
  • JoAnn E. Manson

research papers 2021

Low HDL and high triglycerides predict COVID-19 severity

  • Lluís Masana
  • Eudald Correig
  • the STACOV-XULA research group

research papers 2021

Shorter headed dogs, visually cooperative breeds, younger and playful dogs form eye contact faster with an unfamiliar human

  • Zsófia Bognár
  • Enikő Kubinyi

research papers 2021

Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages

  • Seegehalli M. Anil
  • Nurit Shalev
  • Hinanit Koltai

research papers 2021

The first true millipede—1306 legs long

  • Paul E. Marek
  • Bruno A. Buzatto
  • Juanita Rodriguez

research papers 2021

The poor prognosis and influencing factors of high D-dimer levels for COVID-19 patients

  • Xiaokang He
  • Qingming Wu

research papers 2021

Pruritus is common in patients with chronic liver disease and is improved by nalfurafine hydrochloride

  • Shuhei Yoshikawa
  • Takeharu Asano
  • Hirosato Mashima

research papers 2021

Lethal coalitionary attacks of chimpanzees ( Pan troglodytes troglodytes ) on gorillas ( Gorilla gorilla gorilla ) in the wild

  • Lara M. Southern
  • Tobias Deschner
  • Simone Pika

research papers 2021

Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients

  • Noa Shafran
  • Inbal Shafran
  • Ella H. Sklan

research papers 2021

SARS-CoV-2 virus transfers to skin through contact with contaminated solids

  • Saeed Behzadinasab
  • Alex W. H. Chin
  • William A. Ducker

research papers 2021

The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication

  • Madeline Loffredo
  • Hector Lucero
  • Ali H. Munawar

Ferritin is associated with the severity of lung involvement but not with worse prognosis in patients with COVID-19: data from two Italian COVID-19 units

  • Francesco Carubbi
  • Lia Salvati
  • Davide Grassi

research papers 2021

Outcomes of COVID-19 patients intubated after failure of non-invasive ventilation: a multicenter observational study

  • Annalisa Boscolo
  • Laura Pasin
  • FERS, for the COVID-19 VENETO ICU Network

research papers 2021

The consequences of COVID-19 on social interactions: an online study on face covering

  • Marta Calbi
  • Nunzio Langiulli
  • Maria Alessandra Umiltà

research papers 2021

Dogs distinguish human intentional and unintentional action

  • Britta Schünemann
  • Judith Keller
  • Juliane Bräuer

research papers 2021

Positive Epstein–Barr virus detection in coronavirus disease 2019 (COVID-19) patients

  • Changzheng Chen

research papers 2021

Alarming coastal vulnerability of the deltaic and sandy beaches of North Africa

  • Abderraouf Hzami
  • Essam Heggy
  • Saâdi Abdeljaouad

research papers 2021

Defining priority areas for blue whale conservation and investigating overlap with vessel traffic in Chilean Patagonia, using a fast-fitting movement model

  • Luis Bedriñana-Romano
  • Rodrigo Hucke-Gaete
  • Daniel M. Palacios

research papers 2021

Observation of rescue behaviour in wild boar ( Sus scrofa )

  • Michaela Masilkova
  • Miloš Ježek
  • Hynek Burda

research papers 2021

Time course of the sensitivity and specificity of anti-SARS-CoV-2 IgM and IgG antibodies for symptomatic COVID-19 in Japan

  • Yuki Nakano
  • Makoto Kurano
  • Yutaka Yatomi

research papers 2021

Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration

  • Jennifer K. Frediani
  • Joshua M. Levy
  • Wilbur A. Lam

research papers 2021

Regular intake of energy drinks and multivitamin supplements is associated with elevated plasma vitamin B6 levels in post-bariatric patients

  • Martina Tynes
  • Matthias Hepprich
  • Katharina Timper

research papers 2021

Aggressive behaviour is affected by demographic, environmental and behavioural factors in purebred dogs

  • Salla Mikkola
  • Milla Salonen
  • Hannes Lohi

research papers 2021

In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

  • Yuyong Zhou
  • Kerry Gilmore
  • Peter H. Seeberger

research papers 2021

Anthropogenic drought dominates groundwater depletion in Iran

  • Samaneh Ashraf
  • Amir AghaKouchak

research papers 2021

COVID-19 vaccines that reduce symptoms but do not block infection need higher coverage and faster rollout to achieve population impact

  • David A. Swan
  • Chloe Bracis
  • Dobromir Dimitrov

research papers 2021

A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels

  • Stephan van Vliet
  • James R. Bain
  • Kim M. Huffman

research papers 2021

Detection of volcanic unrest onset in La Palma, Canary Islands, evolution and implications

  • José Fernández
  • Joaquín Escayo
  • Eumenio Ancochea

research papers 2021

Internet memes related to the COVID-19 pandemic as a potential coping mechanism for anxiety

  • Umair Akram
  • Kamila Irvine
  • Jennifer Drabble

research papers 2021

A molecular test based on RT-LAMP for rapid, sensitive and inexpensive colorimetric detection of SARS-CoV-2 in clinical samples

  • Catarina Amaral
  • Wilson Antunes
  • Catarina Pimentel

research papers 2021

Country-level factors dynamics and ABO/Rh blood groups contribution to COVID-19 mortality

  • Alfonso Monaco
  • Ester Pantaleo
  • Roberto Bellotti

research papers 2021

Musical components important for the Mozart K448 effect in epilepsy

  • Robert J. Quon
  • Michael A. Casey
  • Barbara C. Jobst

research papers 2021

Investigation of diets associated with dilated cardiomyopathy in dogs using foodomics analysis

  • Caren E. Smith
  • Laurence D. Parnell
  • Lisa M. Freeman

research papers 2021

Earliest evidence of herd-living and age segregation amongst dinosaurs

  • Adriana C. Mancuso
  • Vincent Fernandez

research papers 2021

Canadian undergraduate men’s visual attention to cisgender women, cisgender men, and feminine trans individuals

  • Lanna J. Petterson
  • Paul L. Vasey

research papers 2021

Brain structure changes associated with sexual orientation

  • Mikhail Votinov
  • Katharina S. Goerlich

research papers 2021

Extreme miniaturization of a new amniote vertebrate and insights into the evolution of genital size in chameleons

  • Jörn Köhler
  • Miguel Vences

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

  • Ayman El-Mohandes
  • Trenton M. White
  • Jeffrey V. Lazarus

research papers 2021

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

  • Harpreet Shinhmar
  • Glen Jeffery

research papers 2021

Modeling the effect of lockdown timing as a COVID-19 control measure in countries with differing social contacts

  • Tamer Oraby
  • Michael G. Tyshenko
  • Mustafa Al-Zoughool

research papers 2021

Identification of CRF89_BF, a new member of an HIV-1 circulating BF intersubtype recombinant form family widely spread in South America

  • Elena Delgado
  • Aurora Fernández-García
  • Michael M. Thomson

research papers 2021

Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain

  • Fabien Dachet
  • James B. Brown
  • Jeffrey A. Loeb

research papers 2021

Effects of cannabis on visual function and self-perceived visual quality

  • Sonia Ortiz-Peregrina
  • Carolina Ortiz
  • Rosario G. Anera

research papers 2021

Particulate matter (PM 2.5 ) as a potential SARS-CoV-2 carrier

  • Norefrina Shafinaz Md Nor
  • Chee Wai Yip
  • Mohd Shahrul Mohd Nadzir

research papers 2021

The effect of ABO blood group and antibody class on the risk of COVID-19 infection and severity of clinical outcomes

  • Marwa Ali Almadhi
  • Abdulkarim Abdulrahman
  • Manaf AlQahtani

research papers 2021

A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States

  • Vibhu Parcha
  • Katherine S. Booker
  • Pankaj Arora

research papers 2021

Climate and the spread of COVID-19

  • Simiao Chen
  • Klaus Prettner
  • David E. Bloom

research papers 2021

Examining the interplay between face mask usage, asymptomatic transmission, and social distancing on the spread of COVID-19

  • Adam Catching
  • Sara Capponi
  • Raul Andino

research papers 2021

Association between coffee and green tea intake and pneumonia among the Japanese elderly: a case-control study

  • Kyoko Kondo
  • Kanzo Suzuki
  • The Pneumonia in Elderly People Study Group

research papers 2021

Discovery of a new mammal species (Soricidae: Eulipotyphla) from Narcondam volcanic island, India

  • Manokaran Kamalakannan
  • Chandrakasan Sivaperuman
  • Kailash Chandra

research papers 2021

Role of IgG against N-protein of SARS-CoV2 in COVID19 clinical outcomes

  • Mayank Batra
  • Runxia Tian
  • Mehdi Mirsaeidi

research papers 2021

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

  • Lisa Mosconi
  • Valentina Berti
  • Roberta Diaz Brinton

research papers 2021

Ivermectin reduces in vivo coronavirus infection in a mouse experimental model

  • A. P. Arévalo

research papers 2021

Excess protein enabled dog domestication during severe Ice Age winters

  • Maria Lahtinen
  • David Clinnick
  • Suvi Viranta

research papers 2021

Psychedelics alter metaphysical beliefs

  • Christopher Timmermann
  • Hannes Kettner
  • Robin L. Carhart-Harris

research papers 2021

Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

  • Carlos Loucera
  • María Peña-Chilet
  • Jose Manuel Quesada Gomez

research papers 2021

Exercise improves the quality of slow-wave sleep by increasing slow-wave stability

  • Insung Park
  • Javier Díaz
  • Kaspar E. Vogt

research papers 2021

Gradual onset of the Maunder Minimum revealed by high-precision carbon-14 analyses

  • Hiroko Miyahara
  • Fuyuki Tokanai
  • Hideyuki Hotta

research papers 2021

Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19

  • Barak Mizrahi
  • Maytal Bivas-Benita
  • Gabriel Chodick

research papers 2021

Satellite mega-constellations create risks in Low Earth Orbit, the atmosphere and on Earth

  • Aaron C. Boley
  • Michael Byers

research papers 2021

Influenza vaccination and the risk of COVID-19 infection and severe illness in older adults in the United States

  • Kelly Huang
  • Shu-Wen Lin
  • Chi-Chuan Wang

research papers 2021

New spinosaurids from the Wessex Formation (Early Cretaceous, UK) and the European origins of Spinosauridae

  • Chris T. Barker
  • David W. E. Hone
  • Neil J. Gostling

research papers 2021

Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration

  • Makoto Takeo
  • Kyosuke Asakawa
  • Takashi Tsuji

research papers 2021

Durability of antibody response to vaccination and surrogate neutralization of emerging variants based on SARS-CoV-2 exposure history

  • Thomas W. McDade
  • Alexis R. Demonbreun
  • Elizabeth M. McNally

research papers 2021

Multiwave pandemic dynamics explained: how to tame the next wave of infectious diseases

  • Giacomo Cacciapaglia
  • Corentin Cot
  • Francesco Sannino

research papers 2021

An international comparison of age and sex dependency of COVID-19 deaths in 2020: a descriptive analysis

  • Peter Bauer
  • Jonas Brugger
  • Martin Posch

research papers 2021

Organic matter and water from asteroid Itokawa

  • Q. H. S. Chan
  • A. Stephant
  • M. M. Grady

research papers 2021

Origin and evolutionary history of domestic chickens inferred from a large population study of Thai red junglefowl and indigenous chickens

  • Mitsuo Nunome
  • Kornsorn Srikulnath

research papers 2021

COVID-19 diagnosis by routine blood tests using machine learning

  • Matjaž Kukar
  • Gregor Gunčar
  • Marko Notar

research papers 2021

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue

  • Melissa Zimniak
  • Luisa Kirschner
  • Jochen Bodem

research papers 2021

Long-term stress in dogs is related to the human–dog relationship and personality traits

  • Amanda Höglin
  • Enya Van Poucke
  • Lina S. V. Roth

research papers 2021

Correlation between CT findings and outcomes in 46 patients with coronavirus disease 2019

  • Guangming Li
  • Guihua Jiang

research papers 2021

Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

  • Tamana Darwish
  • Fiona M. Gribble

research papers 2021

Global prevalence of mental health issues among the general population during the coronavirus disease-2019 pandemic: a systematic review and meta-analysis

  • Surapon Nochaiwong
  • Chidchanok Ruengorn
  • Tinakon Wongpakaran

research papers 2021

Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro

  • Jackelyn Murray
  • Robert J. Hogan
  • Ralph A. Tripp

research papers 2021

UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication

  • Mara Biasin
  • Andrea Bianco
  • Mario Clerici

research papers 2021

The 20-million-year old lair of an ambush-predatory worm preserved in northeast Taiwan

  • Masakazu Nara
  • Shahin E. Dashtgard

research papers 2021

Age constraints for the Trachilos footprints from Crete

  • Uwe Kirscher
  • Haytham El Atfy
  • Madelaine Böhme

research papers 2021

Divergent reflections around the photon sphere of a black hole

  • Albert Sneppen

research papers 2021

The impact of the COVID-19 pandemic on wellbeing and cognitive functioning of older adults

  • Sarah De Pue
  • Céline Gillebert
  • Eva Van den Bussche

research papers 2021

Origin and diffusion of human Y chromosome haplogroup J1-M267

  • Hovhannes Sahakyan
  • Ashot Margaryan
  • Richard Villems

The association of dietary patterns with dietary inflammatory index, systemic inflammation, and insulin resistance, in apparently healthy individuals with obesity

  • Maryam Saghafi-Asl
  • Susan Mirmajidi
  • Vahideh Ebrahimzadeh Attari

research papers 2021

Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

  • Espen Jimenez-Solem
  • Tonny S. Petersen
  • Martin Sillesen

research papers 2021

COVID-19 in South Africa: outbreak despite interventions

  • Malte Schröder
  • Andreas Bossert
  • Jan Schlüter

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  • Part of Cato Institute (Aug. 3, 2021)
  • Part of University of California Press
  • Part of Open: Smithsonian National Museum of African American History & Culture
  • Part of Indiana Journal of Global Legal Studies, Vol. 19, No. 1 (Winter 2012)
  • Part of R Street Institute (Nov. 1, 2020)
  • Part of Leuven University Press
  • Part of UN Secretary-General Papers: Ban Ki-moon (2007-2016)
  • Part of Perspectives on Terrorism, Vol. 12, No. 4 (August 2018)
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COMMENTS

  1. 2021 Top 25 Health Sciences Articles - Nature

    We are pleased to share with you the 25 most downloaded Nature Communications articles* in health sciences published in 2021. (Please note we have a separate collection on the Top 25 COVID-19...

  2. 2021 Top 25 Life and Biological Sciences Articles - Nature

    We are pleased to share with you the 25 most downloaded Nature Communications articles* in the life and biological sciences published in 2021. (Please note we have a separate collection on the...

  3. Journal Top 100 - Nature

    This collection highlights our most downloaded* research papers published in 2021. Featuring authors from around the world, these papers highlight valuable research from an international...

  4. ResearchGate | Find and share research

    Discover research. Access over 160 million publication pages and stay up to date with what's happening in your field.

  5. JSTOR Home

    Enhance your scholarly research with underground newspapers, magazines, and journals. Explore collections in the arts, sciences, and literature from the world’s leading museums, archives, and scholars.

  6. The top 10 journal articles

    In 2021, APA’s 89 journals published more than 5,000 articles. Here’s a quick look at the 10 most downloaded to date.