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61 Great Medical Programs for High School Students + Advice

Extracurriculars

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Thinking about a career in medicine? I highly recommend trying out some medical experiences in high school before committing to a pre-med track . Many of my high school friends who hoped to go into medicine ended up changing their major during college when the pre-med courses got too difficult.

Doing a medical internship, summer program, or community service project in high school can help you decide if medicine is the right track for you before you waste time and money going pre-med in college. This guide will explain what experiences are open to you as a high school student, what those experiences involve, and how you will benefit from them.

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What Medical Experiences Are Available to High School Students?

There are lots of ways to get a taste of what it's like to work in medicine. In my opinion, the best time to do this is over the summer. You have the most free time during the summer, and there are more experiences available.

There are many summer medical programs and summer medical internships for high school students across the country. These opportunities range from research experiences to in-hospital experiences. Some of these programs and internships charge you a fee to attend, some are paid for, and some even pay you to attend.

I've compiled a list of over 60 summer medical programs for high school students. Several of these programs and internships are limited to students from a specific state or area, so be sure to check specific programs for application requirements and fees. I've provided links to each program below.

If you'd like to get experience during the school year (on weekends and after school), you should consider shadowing a doctor or volunteering at a hospital. I'll discuss the details of volunteering and job shadowing later in the article.

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List of Summer Medical Programs for High School Students

I've divided up the summer medical programs into three categories: Medical Programs, Medical Research Programs, and general Science Research Programs.

Medical Programs

In the medical programs category, I list programs that offer high school students the chance to get hands-on experience in medicine (non-research related) such as learning simple medical procedures, watching surgeries, shadowing doctors, working in hospitals, interacting with patients, and more . There are very few programs that offer this type of experience to high school students, and I highly recommend them since they'll give you the most realistic look at what life's like as a pre-med student, medical student, and medical professional.

Cincinnati Children's Hospital Medical Center Cincinnati, OH No cost. Interns are paid $13 an hour 8 weeks
Mentoring in Medicine and Science Oakland, CA $1,400 5 days
National Student Leadership Council Various universities throughout the US $3,795- $3,995 9 days
Stanford University Stanford, CA No cost 5 weeks
Rady Children's Hospital and UC San Diego San Diego, CA $2,800 12 days
University of Pennsylvania Philadelphia, PA $5,700 3 weeks
NSU Florida Fort Lauderdale, FL & Clearwater, FL $1,500 5 days
Tufts University Boston, MA $5,000-$6,500. Some need-based scholarships available 1-2 weeks
Wake Forest University Winston-Salem, NC $3,000 6 days
UCI Urology Orange, CA $4,500-$5,850. Some need-based scholarships available.  12 days

Medical Research Programs

If you're unable to do one of the above medical programs, the next best thing is a medical research program. In these programs, you'll be working in a lab and helping with medical research that's in progress (i.e. looking at slides under a microscope, recording changes) or assisting with on-going clinical research (i.e. interviewing participants in an on-going trial of new medication, logging participant information in the computer). Many of these programs pair you with a mentor who works at your location. Also, several of these programs require you to give a presentation at the end of the program.

These medical research programs are extremely valuable because, as a pre-med student, you'll likely end up doing lab work either for class or as an extracurricular for your medical school application. If you do one of these programs in high school, you'll be a step ahead of your pre-med classmates.

(One quick note: many of these programs are free or pay stipends, but not every program provides free housing . Make sure you check each program's housing accommodations before you apply!)

Buck Institute for Research on Aging Novato, CA No cost; stipend given 10-12 weeks
Centers for Disease Control and Prevention CDC Atlanta, Georgia No cost 5 days
Children's Hospital Colorado Aurora, CO No cost. Interns are paid $3,500 8 weeks
Children's Hospital Oakland Research Institute Oakland, CA No cost. Students get a stipend of $3,000-$4,000 9 weeks
Cincinnati Children's Hospital Medical Center Cincinnati, OH No costs. Interns are paid $13 an hour 9 weeks
Eugene and Ruth Roberts Summer Student Academy Duarte, CA No cost. Students receive a stipend of $4,000 10 weeks
Coriell Institute for Medical Research Camden, NJ No cost. 4 weeks
(Summer Only) Dana-Farber/Harvard Cancer Center Boston, MA No cost; stipend given 8-12 weeks
Indiana University Cancer Center Indianapolis, IN No cost 6 weeks
Max Planck Florida Institute for Neuroscience Jupiter, FL No cost. Students are paid $12/hour 6 weeks
McLaughlin Research Institute Great Falls, MT No cost; stipend given 8 weeks
MD Anderson Cancer Center Houston, TX No cost. Interns are paid $6,000 10 weeks
Medical College of Wisconsin Milwaukee, WI No cost. Students receive a stipend or $10/hour depending on program.  7 weeks
National Cancer Institute Frederick, MD No cost. Students receive a $3,400 stipend 8 weeks
National Eye Institute Bethesda, MD & Rockville, MD No cost. Students receive a monthly stipend (amount varies) 8-12 weeks
NIH Bethesda, MD No cost. Students receive a monthly stipend (amount varies) minimum of 8 weeks
National Institute of Arthritis and Musculoskeletal Diseases Bethesda, MD No cost. Students receive a monthly stipend (amount varies) minimum 8 weeks
NIDA Various universities throughout the US No cost. Interns are paid $15/hour 8 weeks
National Institute of Diabetes and Digestive and Kidney Diseases Bethesda, MD No cost. Students receive a stipend (amount varies) 8-10 weeks
National Institute of Environmental Health Sciences Research Triangle Park, NC No cost. Students receive a stipend or hourly payment depending on program 8 weeks
National Institute of Neurological Disorders and Stroke Bethesda, MD No cost. Students receive a stipend (amount varies) 8-10 weeks
Roswell Park Cancer Institute Buffalo, NY N/A. Limited, need-based subsistence allowances available. 7 weeks
Stanford University School of Medicine Stanford, CA No cost. Students receive stipends from $500 to $1500 8 weeks
The Jackson Laboratory Bar Harbor, ME & Farmington, CT No cost. Students receive a stipend of $6,250 plus room, board, and travel 10 weeks
Translational Genomics Research Institute Phoenix, AZ No cost. Students are paid per hour (salary varies) 8 weeks
University of Connecticut Health Center Farmington, CT $1,401 minimum, with discounts for students who enroll in multiple sessions. Limited need-based scholarships and discounts available.  1-5 weeks
University of Minnesota Medical School, Lillehei Heart Institute Minneapolis/St. Paul, MN No cost. Students receive a stipend (amount varies) 9 weeks
University of Nebraska Medical Center, Department of Pharmacology & Experimental Neuroscience Omaha, NE No cost. Students receive a stipend of $1,500 with preference given to students from Nebraska and surrounding areas up to 10 weeks
University of Texas Medical Branch Galveston, TX No cost 1 week
Wistar Institute Philadelphia, PA No cost. Students receive a stipend of $1,000 at end of program.  4 weeks
Magee-Womens Research Institute & Foundation  Pittsburgh, PA No cost. Students receive a stipend (amount undisclosed)  4 weeks
Harborview Injury Prevention & Research Center, University of Washington Seattle, Washington $2,200 4 weeks

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Science Research Programs

If you can't do one of the medical research or medical programs, you should consider trying to do a science summer program/internship . These programs are not medicine-specific and cover a wide range of science topics (from plant life to space). However, these programs are still very valuable because as a pre-med student, you'll be learning a ton of science. As a part of your pre-med track, you'll be required to take Biology, Chemistry, Biochemistry, Organic Chemistry, and more. Doing one of these science programs will give you a preview of the coursework ahead of you.

Also, many of these programs are lab work, and, although they're not focused on medical research, they will still give you good general insights into how to do lab work . As I said before, as a pre-med student, you'll likely end up doing lab work either for class or as an extracurricular for your medical school application. If you do one of these programs, you'll be well-prepared to do that research.

George Mason University Fairfax, Virginia No cost 8 weeks
Department of Defense Washington, DC Varies. Some scholarships and grants are available Varies depending on program
J. Craig Venter Institute Rockville, MD No cost. Students are paid hourly. 10-15 weeks
Maine Space Grant Consortium Augusta, ME No cost. Students earn a stipend (amount undisclosed) 6 weeks
Massachusetts Institute of Technology - MIT Cambridge, MA No cost 6 weeks
Monell Chemical Senses Center Philadelphia, PA No cost 7 weeks
Monmouth University West Long Branch, NJ No cost. Students are paid about $14.13 per hour 10 weeks
Museum of Science Boston, MA No cost. Positions can be paid or unpaid, depending on program Varies
National Aeronautics and Space Administration Greenbelt, MD & Wallops Island, VA No cost. Students received a stipend of $2,400 6 weeks
Ohio Agricultural Research and Development Center Wooster, OH No cost. Students are paid $12/hour 10 weeks
Saturday Academy Oregon & Southwest Washington Varies 8 weeks
Scripps Research Institute La Jolla, CA No cost. Students are paid $4,760 9 weeks
University of Maryland College Park, MD $300-$400 2 weeks
State University of New York College at Oneonta Cooperstown, NY No cost. Interns receive a stipend of $3,000 10 weeks
The Forsyth Institute Boston, MA No cost. Students are paid an hourly wage (amount varies) 8 weeks
University of Maryland Eastern Shore, Living Marine Resources Cooperative Science Center Princess Anne, MD No cost. Students are paid $500 per week 6 weeks
University of Wyoming Laramie, WY Varies depending on program Varies depending on program
Stony Brook University Stony Brook, NY No cost 7 weeks
Boston University Boston, MA $5,100. A limited number of need-based scholarships are available 6 weeks

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What Are the Pros and Cons of These Programs?

These medical programs can be a great experience for many high school students, but they can have some drawbacks. In this section we'll look at the pros and cons of medical programs for high school students.

  • These programs and internships provide a real look at what life's like as a researcher, scientist, or medical student. You'll have a great sense of whether or not you'd like to pursue a career in the medical field after you finish your program.
  • If you do a college campus program, you'll get a preview of college life . You can experience living away from home, and you can decide if you like the college. I did a summer program at UCLA during high school, and it made me realize that UCLA was not the school for me.
  • As I said before, these opportunities give you the chance to evaluate if pre-med is the track you want to go down before you waste time and money in college. If you love your program, you'll be even more motivated to work hard to become a medical professional .
  • You'll meet like-minded students who're interested in medicine/science.
  • You'll have a great program or internship on your college application . By actually participating in a medical/science program, you'll show colleges that you're committed to pursuing a career in the medical field.
  • If you attend a college campus program, and you're interested in going to college at the school that hosted the program, you'll have shown real interest in that college (which admissions officers always like to see).
  • These programs can be expensive . However, some programs pay you to attend! Make sure you check out the individual program websites to find out the cost. And like we mentioned before, pay careful attention to housing! Some programs might offer stipends, but they may not cover housing or transportation costs.
  • Also, these summer medical programs for high school students can be highly competitive (some admit very few students or have special qualifications such as having a 3.5 GPA or higher).
  • Some programs may not provide you with the best insight into medicine , especially those that are less hands-on or only offer research exposure (which is not what you'll necessarily be interested in).

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Other Options: Hospital Volunteer or Shadowing a Doctor

Volunteering and job shadowing are both great ways to participate in medical experiences at your local hospital. You can do them during the school year or the summer. Also, both opportunities are free!

What's the difference between volunteering & job shadowing a doctor? As a hospital volunteer, you'll have to apply (and likely interview) to be a volunteer (along with getting a TB test and filling out paperwork). You'll attend a hospital volunteer orientation and be assigned a specific "job" at the hospital, such as assisting the nurses or assisting hospital visitors in navigating the hospital. As a volunteer, you'll be required to commit to volunteering for a certain number of shifts per week. You also may have to commit to volunteering for six months or more.

Job shadowing is a shorter experience and much less formal. You can shadow a doctor for as little time as a few hours or a day or two. While shadowing, you follow a doctor around while they go about their normal activities. They may ask you to help them with basic tasks (grabbing a chart or taking notes), but probably not. You'll be there to see what a doctor does in their daily routine to determine if it interests you.

To sign up to be a hospital volunteer, apply through the hospital's website. If you're having trouble locating the hospital's website or contact information, check with your school academic advisor. They may have a connection to the local hospital or might know another student who has volunteered or job shadowed there and who could help you get involved.

To find a job shadowing opportunity, reach out to any friends or family who work in the medical field. See if they know any doctors whom you could shadow. Also, ask your school's academic advisor if they know other students who shadowed a doctor and could give you more information. If your school can't help you, get in touch with the hospital directly to see if they can help you set up a job shadowing opportunity. If you need more advice on job shadowing, read our other guide.

What Are the Pros and Cons of Shadowing a Doctor or Being a Hospital Volunteer?

Shadowing a doctor or being a hospital volunteer is a significantly different experience than participating in a summer medical program, and they have their own set of pros and cons.

  • As opposed to summer programs, these experiences are always free. As I said above, some medical programs and internships can cost a lot of money. Job shadowing and being a hospital volunteer are free experiences that will only cost you your time. These are great options if you can't afford the cost of a summer program.
  • Job shadowing and being a hospital volunteer can provide a real look into life as a doctor or nurse. By following them around or working in a hospital, you'll get a sense of the work environment and what life is like on a day-to-day basis for a medical professional.
  • As I said before, these opportunities give you the chance to evaluate if pre-med is the track you want to go down before you spend time and money in college. If you don't like your experience job shadowing or as a volunteer, you might realize pre-med isn't the right path for you. However, if you love your experience, you'll feel more motivated to work towards your goal of becoming a medical professional.
  • Job shadowing is a great experience if you don't have a lot of time to commit. You can choose to job shadow for a few hours, a full day, or for several days. It's very flexible.
  • If you want to be pre-med, volunteering at a hospital is a great extracurricular activity for your college application. While volunteering elsewhere (at a homeless shelter, animal shelter, etc.) can be great for a college application, it's good to keep your extracurriculars focused on your future goals. Volunteering at a hospital will show colleges that you're serious about a career in medicine.
  • Volunteer experience may not provide you with quite the medical experience you're looking for. Volunteering may not be very hands-on, and your duties may be repetitive and not directly related to medicine, such as answering phones, filing papers, and helping visitors find where they're going.
  • If you only job shadow for a day, it's not a great experience for your college application. It's not an extracurricular activity if you only do it once because that doesn't show enough commitment. However, I recommend doing job shadowing just to get insight into the medical field.

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How to Choose the Right Medical Experience for You

Each of the medical experiences listed in this article has value, but to decide which is right for you, you should ask yourself three questions:

#1: What Is Your Main Medical Interest?

Are you more interested in research or patient care? If research, look into one of the summer research programs. If patient care, look into one of the hospital-based programs, job shadowing or being a hospital volunteer.

#2: How Much Money Are You Willing to Spend?

Do you have money to spend, do you have no money to spend, or do you need to have a job that pays? If you have money to spend, you can consider all of the options. If you have no money to spend, look into an all-expenses paid program (or one with financial aid). Also, consider volunteering or job shadowing since both are free experiences. If you need a job that pays, look into the programs with stipends for participants.

#3: How Much Time Do You Want to Invest in Your Experience?

Do you want to spend a day, a few hours per week, or a few weeks full-time on this experience? If you want a quick experience, consider job shadowing a doctor for a day or two. If you'd like an on-going experience to use as an extracurricular, consider volunteering since you could do that a few hours per week throughout the school year. If you'd like an intensive experience, consider doing one of the summer programs or internships.

Also, always make sure to research a program or experience before you commit to it. Doing so will help avoid a bad experience (such as a program that's not very hands-on or volunteer work that's mostly grunt work). Whatever you're interested in doing, try to find another student who did it previously and ask them about their experience. For the programs, get in touch with the program coordinator to see if they can put you in contact with a program alum you can speak with.

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College take a close look at your extracurriculars. Like, a really close look.

How Will Colleges View These Experiences?

Colleges mainly look for extracurriculars that show your commitment, passion, and ability to handle responsibility and leadership. Job shadowing isn't a great experience for your college application because it's not enough of a commitment if you only do it for a few days. On the other hand, volunteering at a hospital is a great extracurricular activity for your college application because it shows a commitment to medicine.

The summer programs and internships are also great experiences for your college application because they show that same interest in and commitment to medicine. Also, many of these programs and internships are competitive, and colleges know that. If you're accepted into one of those programs or internships, colleges will view it like you won a prestigious award.

What's Next?

Doing a medical program is a great step, but what else do you need to do to prepare for med school? Check out our step-by-step guide to preparing for med school as a high school student and our list of the best books for pre-med students .

Also, you should learn about how to write about extracurriculars on college applications . Check out four amazing examples of extracurriculars for college applications.

Interested in a BS/MD program? They can be a great way to save some time and get your medical degree sooner. Read our guide on getting into BS/MD programs to learn more.

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Stanford institutes of medicine summer research program, program description.

The Stanford Institutes of Medicine Summer Research Program (SIMR) is an eight-week program in which high school students with a broad range of experiences, interests and backgrounds are invited to perform basic research with Stanford faculty, postdoctoral fellows, students and researchers on a medically-oriented project. The goals of the program include increasing interest in biological sciences and medicine in high school students and helping students to understand how scientific research is performed.

ELIGIBILITY REQUIREMENTS  

ALL 3 of the following requirements must be met (no exceptions):

1) Students must currently be juniors or seniors at the time of application (as of the spring of 2024).  Students must be in the graduating class of 2024 or 2025.

2) Students must also be  16 years old or older  by the start of the program.

3)  Students must currently be living in and attending school in the U.S. AND must be  U.S. citizens or permanent residents  with a green card in order to apply.

Important Note:  Please read the MISSION link on the lefthand panel.  The selection process will heavily favor local (Bay Area) students. Please visit the FAQ for more information.  Also, students must be able to start the program on June 10, 2024.  

SUMMER 2024 UPDATE:

  • The current plans are to have an in-person program for the summer of 2024.  
  • Summer 2024 Program Dates:  June 10- August 1, 2024 (8 weeks)
  • The online application and program information document will be available on our website on Wednesday, Dec. 20th, 2023 (at 5pm PST) .  Applications will be due Saturday, February 24th, 2024.

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20 Medical Science Programs for High School Students

how to do medical research in high school

By Eric Eng

student doctors sitting around a table while one of them is looking at the camera smiling

Are you a high school student dreaming of a career in medicine? Navigating the path to a successful medical career can seem challenging, but it’s an exciting journey that starts right in high school. In this blog, you’ll discover 20 outstanding medical science programs specifically designed for high school students like you. These programs offer unique opportunities to explore the medical field, gain valuable knowledge, and set a strong foundation for your future.

Whether you’re aiming for a top-tier college or looking to ignite your passion for healthcare, these programs are stepping stones to achieving your dreams.

1. Stanford Medical Youth Science Program

  • Location: Stanford University
  • Program Date: June 24–July 26, 2024
  • Application Deadline: March 15, 2024
  • Eligibility: Low-income and/or underrepresented minority high school sophomores and juniors

The Stanford Medical Youth Science Program (SMYSP) offers a dynamic and immersive five-week enrichment experience for high school juniors who are first-generation and from low-income backgrounds in Northern California. As a participant, you will delve into a comprehensive curriculum that includes hospital internships at Stanford Hospital and a public health research project. The hospital internships provide you with hands-on experience in various aspects of healthcare delivery.

In addition to these practical experiences, the program emphasizes mentorship and community building. You’ll receive guidance and support from faculty, health professionals, and college students, fostering a network that extends beyond the summer. The program also includes academic seminars and lectures covering public health, research methodology, and human anatomy, conducted by Stanford medical students. These sessions are designed to prepare you for your research project and provide insights into college and medical school preparation.

Medical interns

One of the most significant aspects of SMYSP is that it’s tuition-free, and aimed at increasing opportunity and access for aspiring first-generation college students. You’ll be expected to commit full-time Monday through Friday, gaining a deeply enriching educational experience. Moreover, the program includes a stipend for clinical research, further supporting your journey in science and medicine.

2. Health Career Institute at Dartmouth

  • Location: Dartmouth College
  • Cost: $2,800 – $3,600
  • Program Date: June 24-29, 2024
  • Application Deadline: March 16, 2024
  • Eligibility: Students entering 11th and 12th grades

The Health Careers Institute at Dartmouth is a unique and enriching opportunity for high school students interested in exploring a variety of disciplines within the healthcare sector. Scheduled for June 24-29, 2024, this program is specifically designed for students entering 11th and 12th grades who are keen on delving into healthcare careers and eager to learn about both clinical and non-clinical health professions​​​.

At the institute, you’ll have the chance to interact with a range of professionals in the healthcare system, including physicians, research scientists, and experts in public health and health policy. This exposure is invaluable in understanding the complexities of healthcare systems and policies. The institute’s faculty comprises experienced healthcare professionals from Dartmouth and other educational and health institutions, offering you mentorship and insights that extend beyond traditional classroom learning​.

The program’s structure includes classroom instruction, a team-based research project, and dialogues with faculty and health profession students, ensuring a comprehensive learning experience. Importantly, you’ll also get a taste of college life by living in a dorm on the Dartmouth College campus and engaging in discussions about the college application process, which can be particularly beneficial for your future academic pursuits​.

3. Summer Student Research Program at UCSF Benioff Children’s Hospital Oakland

  • Location: MLK. Research Building in Oakland, UCSF Benioff Children’s Hospital
  • Cost: $3000–$4300
  • Program Date: Early June to early August (specific dates unspecified)
  • Application Deadline: February 16, 2024
  • Eligibility: Students over 16 years of age

One of the medical science programs for high school students, the Summer Student Research Program at UCSF Benioff Children’s Hospital Oakland is a remarkable opportunity for high school and college students, especially those from diverse and under-represented backgrounds, to engage in biomedical research. This program, with a history spanning over 40 years, integrates students into local clinics and basic science labs, where they participate in active research projects. As a participant, you’ll be paired with a mentor for one-on-one guidance through clinical or basic science research projects, which vary greatly depending on the mentor you’re assigned.

Group of medical students in college hallway

To be eligible, you need to be a high school junior or senior with at least one completed year in math and biology, or an undergraduate student. It’s important to be at least 16 years of age by June 1st of the program year. A key focus of the program is to encourage students from underrepresented groups in the sciences to pursue STEM careers by providing them with professional skills and confidence. Participants also receive a stipend, which varies based on student status and the granting agency​​​​​.

4. Arthritis Foundation Summer Science Internship Program

  • Location: University of California, San Francisco
  • Cost: Unspecified
  • Program Date: May 28 – August 30, 2024
  • Application Deadline: March 4, 2024
  • Eligibility: Students over 17 years old

The Arthritis Foundation Summer Science Internship Program offers a dynamic opportunity for high school juniors, seniors, and college undergraduates interested in exploring the fields of rheumatology and immunology, with a particular focus on arthritis and related autoimmune diseases. Hosted by the prestigious University of California, San Francisco (UCSF), and Stanford University, this 8-week program, running from May 28 to August 30, 2024, immerses you in cutting-edge research environments​​​​​​​.

During the internship, you will engage in hands-on experiences in either basic laboratory (bench) research, clinical translational/epidemiological (patient-oriented) research, or bioinformatics (computational) research. This program is a great opportunity to delve into the intricacies of conditions like arthritis, understand the body’s immune responses, and contribute to the development of effective treatments. Not only will you gain valuable insights from world-renowned physicians and scientists, but you will also receive a stipend of $2,500 for your participation. To be eligible, you must be at least 17 years old by the start of the program and a citizen or permanent resident of the USA​​​​​​​​.

5. Health and Society Institute at Barnard College

  • Location: Barnard College
  • Cost: $7,772 – $9,687
  • Program Date: July 22 – August 10, 2024
  • Application Deadline: May 26, 2024
  • Eligibility: Juniors and seniors in high school

The Health and Society Institute at Barnard College offers an insightful and immersive program that investigates the intricate relationship between health, society, and science. This program stands out for its dedication to exploring the cultural, historical, and economic underpinnings of the U.S. healthcare system. You’ll delve into how scientific knowledge interacts with other forms of knowledge representation and evaluate the credibility and influence of experts in various fields.

Barnard College

A unique aspect of the program is its emphasis on qualitative research. You will gain foundational knowledge and techniques related to qualitative research, including conceptualizing, planning, and implementing research projects. This experience is not just about learning; it’s about applying these skills to real-world scenarios, particularly in the context of working with human subjects.

6. Agress Summer Health Corps Program

  • Location: Beth Israel Deaconess Medical Center
  • Program Date: July 1 to August 8, 2024
  • Application Deadline: December 31, 2023​​​​
  • Eligibility: High school students

One of the medical science programs for high school students, the Agress Summer Health Corps Program is a unique, hands-on educational opportunity hosted by the Beth Israel Deaconess Medical Center. Running for six weeks in July and August, this program is tailored for high school students, providing them with an immersive experience in various healthcare careers within a hospital setting. In 2024, the program will take place from July 1 to August 8, with mandatory orientation on the first day and a closing banquet on the last. The daily schedule is set from 9:00 am to 2:00 pm, starting from July 2​​​​.

During the program, you will work alongside experienced healthcare professionals, including doctors, nurses, and researchers. This exposure not only offers a real-world view of the healthcare industry but also allows you to learn from and interact with seasoned professionals, thereby gaining valuable insights into different roles and responsibilities. It’s a chance to see where your interests and aptitudes lie within the healthcare sector. Additionally, the program fosters a community of peers who share your passion for healthcare, creating an environment for collaboration and networking.

7. Summer Program In Neuroscience

  • Location: Boston University
  • Cost: $4,000
  • Program Date: June 3 – July 25, 2024
  • Application Deadline: March 18, 2024
  • Eligibility: Junior and senior undergraduate students

The Summer Program in Neuroscience (SPIN) at Boston University is an eight-week program designed for undergraduates with an interest in neuroscience, biomedical engineering, computer science, and medicine. SPIN combines research activities with clinical and didactic experiences to provide a comprehensive understanding of neuroscience. Students participate in hands-on neuroanatomy labs, attend small group lectures, and are involved in clinical rotations that include observing neurosurgical procedures and neurological assessments.

This program not only enhances understanding of the brain and neuroscience research but also supports career development with sessions on application processes for medical and graduate schools and interview skills. Admission is based on academic performance, letters of recommendation, and a personal statement. The program runs from June 3 to July 25, 2024, with a tuition cost of $4,000, not including room and board. The application deadline for 2024 is March 18th.

8. High School Scientific Training and Enrichment Program

  • Location: NIH Main Campus, Bethesda, Maryland
  • Program Date: July 2 – August 1, 2024
  • Application Deadline: January 12, 2024
  • Eligibility: Rising 12th graders

The High School Scientific Training and Enrichment Program (HiSTEP) is a distinctive opportunity for rising 12th graders, particularly those from schools where a significant portion of students are enrolled in the Federal Free and Reduced Lunch Program. Located at the NIH main campus in Bethesda, Maryland, the program spans from July 2 to August 1, 2024, requiring a commitment of at least 21 hours per week every Tuesday through Thursday. It’s designed for students with a cumulative GPA of 3.0 or higher, though those with a GPA between 2.75 and 3.0 are also encouraged to apply if they have shown steady academic improvement​.

students listening and talking to male teacher

HiSTEP focuses on introducing participants to biomedical research and healthcare careers through various activities such as lectures, visits to research groups, networking events, small group discussions, and group projects. Additionally, the program guides the college application process, and helps develop career readiness and leadership skills, along with a resilience and well-being program.

Applicants must be U.S. citizens or permanent residents and live within 40 miles of the main NIH campus. The program emphasizes diversity and inclusion, encouraging applications from underrepresented racial and ethnic groups, those with disabilities, LGBTQ+ individuals, and those disadvantaged by life circumstances that have negatively impacted their educational opportunities​​​.

9. Neuroscience Research Academy

  • Location: The University of Pennsylvania
  • Cost: $9,700
  • Program Date: July 6 – July 27, 2024
  • Application Deadline: February 15, 2024
  • Eligibility: Students with at least one year of high school biology

One of the medical science programs for high school students, the Neuroscience Research Academy delves into the biological underpinnings of the brain, covering topics ranging from the fundamental cellular aspects of neurons to an exploration of sensory systems. It ultimately delves into more complex cognitive functions like memory, emotions, and moral reasoning.

Instructed by faculty from Penn’s Biological Basis of Behavior program , this academy offers students an opportunity to immerse themselves in the forefront of research and medical advancements in the field. This area of study has contributed significant insights into comprehending the mind’s workings in both healthy and diseased states. Please note that participation in the Neuroscience Research Academy requires full-time residential attendance, and there are no options for commuting or online participation.

10. NIH Summer Internship Program

  • Location: Bethesda, Maryland and Framingham, Massachusetts
  • Program Date: Between May and September 2024
  • Eligibility: Students at least 17 years of age

The NIH Summer Internship Program (SIP) is an exceptional opportunity for college, graduate, and professional students who are keen on exploring careers in research and healthcare. As a participant, you’ll be working full-time within one of the NIH Institutes and Centers in the Intramural Research Program. The research groups are spread across NIH campuses, including the main campus in Bethesda, MD.

Eligibility for the program is fairly broad. You must be a U.S. citizen or permanent resident, 17 years or older by June 15, 2024, and enrolled at least half-time in an accredited educational institution. This includes community colleges, colleges, universities, or professional schools. The program also has specific stipulations for U.S. permanent residents regarding their educational institution. In addition to the academic and citizenship requirements, participants are also expected to present proof of health insurance. The application process for the SIP is comprehensive, requiring a detailed profile, a list of coursework and grades, a CV or resume, references, and a cover letter. The selection process is thorough, with a focus on aligning applicants’ research interests with ongoing projects​​​​.

11. High School Summer Research Experience at Roswell Park

  • Location: Roswell Park Comprehensive Cancer Center, Buffalo, New York
  • Program Date: June 24 – August 9, 2024
  • Application Deadline: February 21, 2024
  • Eligibility: Students at least 15 years of age

The High School Summer Research Experience at Roswell Park offers an invaluable opportunity for high school juniors to delve into the world of scientific research, specifically focused on cancer science. Set to run from June 24 to August 9, 2024, this program allows you to work alongside experts on your own independent research project.

Multiracial university students

To be eligible for this program, you must be enrolled as a junior in high school at the time of your application and be a resident of Western New York. The program is a commuter-based one, which means you’ll need to travel to the facility daily, as there are no accommodations for staying on-site. Applicants must be either U.S. citizens or U.S. permanent residents and at least 15 years old by the start of the program. Notably, all participants will be required to provide proof of full vaccination against COVID-19. If accepted, you can expect to engage in advanced research topics, enhancing your understanding of scientific processes and methodologies, which is pivotal for anyone considering a future in science or healthcare​​​​​.

12. Stanford Institutes of Medicine Summer Research Program

  • Location: Stanford University’s Institutes of Medicine
  • Program Date: June 10 – August 1, 2024
  • Application Deadline: February 24, 2024
  • Eligibility: High school juniors and seniors

The Stanford Institutes of Medicine Summer Research Program (SIMR) is an eight-week summer internship designed for high school juniors and seniors interested in biomedical research. Scheduled for June 10 to August 1, 2024, the program offers hands-on research experience under the guidance of mentors at Stanford University’s Institutes of Medicine and select departments. Applicants to SIMR can choose from eight research areas, including Immunology, Neurobiology, Cancer Biology, Bioengineering, Stem Cell and Regenerative Medicine, Cardiovascular Biology, Bioinformatics, and Genetics and Genomics. The program also offers a bioengineering bootcamp as an alternative to the lab research component​​​​.

In addition to the research experience, SIMR emphasizes skill-building and professional development, such as lab techniques, data analysis, teamwork, and research presentation skills. The program includes seminars and workshops to broaden your understanding of biomedical career options. A key aspect of SIMR is its commitment to inclusiveness and diversity, welcoming students from various backgrounds and enriching the research environment with diverse perspectives.

13. UPenn Biomedical Research Academy

  • Location: Penn’s School of Medicine

The UPenn Biomedical Research Academy is a comprehensive program for high school students interested in exploring the experimental basis of cellular, molecular, and genetic aspects of biology, particularly focusing on their relevance to diseases. Scheduled to run from July 6 to July 27, 2024, this program is designed as a fully residential experience where you’ll be immersed in daily lectures, faculty research talks, laboratory experiments, and small group investigations. The course content includes a wide range of topics such as genome sequencing, CRISPR/Cas-9, vaccines, antibiotic resistance, and bioethics, delivered by scientists, clinicians, and faculty from the Department of Biology and Penn’s School of Medicine.

View of UPenn sign

In the laboratory component, you’ll get to perform experiments using techniques like PCR, gel electrophoresis, restriction analysis, bacterial transformation, and ELISA. You’ll have the opportunity to work on projects such as determining your blood type and investigating gene expression in bacteria. The program also includes journal clubs where you’ll engage in discussions on peer-reviewed research articles, learning how to read, interpret, analyze, and critique primary research under the guidance of Penn researchers or faculty members. This setup not only offers deep insights into the core of biomedical research but also equips you with valuable skills and knowledge for your future academic or professional endeavors in the field of biology​​​​​.

14. Neuroscience Camp at Drexel

  • Location: Drexel University
  • Cost: $2,200
  • Program Date: July 8–19, 2024
  • Application Deadline: April 15, 2024
  • Eligibility: High school sophomores and juniors

The Neuroscience Camp at Drexel University,  one of the medical science programs for high school students, is a highly esteemed program designed for high school sophomores and juniors with a keen interest in neuroscience. To be eligible for this competitive program, you should be a rising junior or senior with a background in biology, chemistry, or research. The application process requires you to submit transcripts and two letters of recommendation, with an application deadline set for April 15, 2024. The cost of the camp is $2,200, and it’s important to note that this is not a residential program, so housing is not provided.

During the camp, you will engage in an intensive study of neuroscience under the guidance of Drexel University College of Medicine’s esteemed faculty members, Dr. Jed Shumsky and Dr. Michael Lane. The curriculum includes a wide range of neuroscience topics, such as cellular neuroscience, neuropharmacology, electrophysiology, and other advanced subjects. Hands-on experiences, like live brain activity recordings, are a core component of the camp. You’ll also have the opportunity to undertake a lab project encompassing various neuroscience laboratory techniques and data analysis.

15. Eugene And Ruth Roberts Summer Student Academy

  • Location: City of Hope, Duarte CA
  • Program Date: June 3 – August 9, 2024
  • Application Deadline: March 13, 2024
  • Eligibility: High school and undergraduate students

The Eugene and Ruth Roberts Summer Student Academy at City of Hope offers you a chance to gain hands-on research experience in biomedical science. This program, aimed at high school and undergraduate students, provides a unique opportunity to work on real-world research projects.

You must be at least 16 years old to participate, and while it’s beneficial to submit additional materials like transcripts and recommendation letters, these are not strictly required. The program spans ten weeks and requires you to contact the program administrator for specific time period details. This academy is a great way to immerse yourself in the world of scientific research, especially if you have a keen interest in biomedical fields.

16. Research Training Program for High School Students

  • Location: Seattle Children’s Research Institute
  • Program Date: July 8–August 2, 2024
  • Application Deadline: March 10, 2024
  • Eligibility: Rising high school juniors and seniors

The Research Training Program for High School Students at Seattle Children’s Research Institute is a comprehensive program designed for students interested in exploring the world of biomedical research. It’s crucial that you are interested in fields like biology, biochemistry, microbiology, or public health, but prior knowledge in these areas is not required. A notable aspect of this program is its commitment to diversity and inclusion, especially encouraging participation from underrepresented groups in the biomedical and health sciences.

student in front of university building looking at camera

The program, one of the medical science programs for high school students, which runs from July 8 to August 2, 2024, offers a mix of educational lectures, hands-on laboratory experiences, and career workshops. You’ll be engaged in activities like microscopy, agarose gel electrophoresis, and gene editing, among others. Additionally, the program includes tours of the facility and a group research project, culminating in a presentation. This experience is not only about gaining laboratory skills but also about understanding the application process for college and exploring various career paths in biomedical fields.

Applications for the program open in early January and close in March. You will need to submit an application form and a letter of recommendation. Keep in mind that the program is competitive, and being within commuting distance of downtown Seattle is necessary, as housing is not provided. Importantly, participants will receive a stipend, and thus a Social Security Number is required for tax purposes.

17. Biomedical Research and Global Health at Seattle Children’s Institute

  • Location: Seattle Children’s Institute
  • Program Date: 2023-2024 school year
  • Application Deadline: March 8, 2024
  • Eligibility: 11th and 12th-grade students

The Biomedical Research and Global Health program at Seattle Children’s Institute, in partnership with the Highline School District, is one of the medical science programs for high school students that offers an immersive year-long academic experience for high school students. This program is tailored to prepare you for a variety of career opportunities in biomedical research and healthcare. Throughout the program, you will engage in hands-on lab experiences, providing an authentic introduction to the research process.

These experiences include learning lab safety, practicing essential lab skills, and using state-of-the-art equipment for experiments related to disease prevention and treatment. Additionally, guest lectures from scientists and field trips to local research organizations will give you an inside look into careers in this rapidly evolving field.

The program is designed to build a robust foundation in biological sciences and research, integrating modern advancements in technology, such as gene editing and immunotherapy. You will be exposed to real-world scenarios and have opportunities for professional development and career planning.

18. Summer Scholars Program (SSSP)

  • Program Date: June 18 – August 16, 2024
  • Eligibility: Undergraduate students

One of the medical science programs for high school students, the Summer Scholars Program (SSSP) at Seattle Children’s Research Institute is an enriching opportunity for undergraduate students and recent graduates, especially those from backgrounds historically underrepresented in biomedical and health sciences. This 10-week program allows you to engage in basic, clinical, or translational research projects under experienced mentorship. You can earn $20 per hour for a 40-hour week, though taxes will be withheld from this income. The program, slated to run from June 18 to August 16, 2024, requires your full-time commitment, including additional hours for professional development activities.

Young curly student woman wearing backpack glasses holding books

In the SSSP, you will gain hands-on lab experience, ranging from using lab equipment and software for research projects to attending career and professional training sessions. These sessions cover essential topics like abstract writing, research poster presentations, and networking strategies. Throughout the program, you will work closely with mentors, helping you build vital research skills. By the end of the program, you will have the opportunity to publish an abstract and present your findings at a poster symposium.

19. The Neuroscience Summer Institute at Carleton

  • Location: Carleton College
  • Cost: $4,500
  • Program Date: July 6–26, 2024
  • Application Deadline: March 11, 2024

The Neuroscience Summer Institute at Carleton, scheduled for July 6-26, 2024, is an engaging three-week program designed to provide a comprehensive introduction to the field of neuroscience. In this program, you will participate in an intensive “Introduction to Neuroscience” course, which will expose you to various aspects of neuroscience, including brain anatomy, physiology, and chemistry.

The program is not just about lectures; it includes hands-on laboratory activities, such as sheep brain dissection, behavioral testing, microscope work, and data analysis. You’ll even get exposure to advanced techniques like small animal brain surgery. Furthermore, the program includes opportunities to tour other neuroscience labs, allowing you to explore a wide range of research areas in the field. The program culminates with a symposium where you will present your work to peers and the broader community.

As a participant, you will earn up to six Carleton course credits (transferring as three-semester credits) for successfully meeting faculty expectations and completing course requirements. You’ll receive a grade and have the option to request a formal academic transcript to reflect your achievements in the program. This experience at Carleton’s Summer Program, also known as “Summer Carls,” is an excellent way to delve into the fascinating world of neuroscience while earning college credits​​​​​.

20. Institute On Neuroscience

  • Location: Emory University
  • Cost: $25 application fee
  • Program Date: Exact dates for 2024 not specified
  • Application Deadline: Unspecified
  • Eligibility: High school juniors or seniors

The Institute on Neuroscience (ION) at Emory University , in collaboration with the Yerkes National Primate Research Center, The Marcus Autism Center, and Georgia State University’s Center for Behavioral Neuroscience, offers an enriching eight-week summer program for high school students. This is one of the medical science programs for high school students that’s designed for students who excel in science and have a keen interest in neuroscience research.

The ION program begins with a Meet-the-Mentor Luncheon in the spring, followed by a one-week introductory curriculum in early June. During this period, you will learn about neuroscience through hands-on activities, discussions, and readings directed by faculty members, post-doctoral researchers, and undergraduate and graduate students. The program also includes visits to research facilities to learn about various techniques like PET scanning or electron microscopy. Additionally, you’ll engage in Friday workshops focusing on scientific communication, science and society, scientific ethics, and special topics in neuroscience.

Two college students standing in corridor

After the introductory week, you will conduct a seven-week mentored laboratory research project at one of the participating institutions. The summer concludes with a comprehensive Closing Research Symposium, where you will be required to present your research findings in a 10-minute slide presentation to an audience including family, friends, peers, program mentors, and others in the neuroscience community. This presentation is a celebration of your hard work and achievements throughout the program.

Final Thoughts

As you look towards your future in medicine, remember that the journey is as important as the destination. The medical science programs for high school school students we’ve explored are more than just a line on your college application; they’re gateways to understanding, opportunities to grow, and platforms to showcase your commitment and passion. Embrace these experiences, and let them guide you to a fulfilling career in healthcare. Your journey has just begun, and the possibilities are endless. Stay curious, stay dedicated, and let your passion for medicine light the way to a bright future.

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62 Best Research Opportunities for High School Students

June 2, 2024

Hands-on laboratory-based research experiences are coveted by just about every STEM-oriented teenager on the planet. Of course, this level of demand renders research opportunities for high school students a valuable and rare commodity. Fortunately, there are a number of reputable summer programs run by universities, government agencies, and private research laboratories that afford young scientists this highly sought-after experience. Research opportunities during the actual school year are more challenging to locate as colleges are, at that time, catering to their own students, and the rigidity of the high school calendar makes participation a further challenge.

What type of research opportunities can a high school student have, anyway?

Research opportunities for high school students can range from introductory to highly advanced. Some programs focus on teaching students the fundamental skills required for research while others place students with a real working research group and allow them to contribute to legitimate experiments and papers. Your level of involvement will depend on the university or organization’s policies, your mentor, your lab team, and the type of research being conducted.

What types of research experiences look best on college applications?

Authentic, laboratory-based research experiences that you get paid for are the hardest types of positions to nail down, primarily because very few of these spots are available. Moreover, such research groups are conducting serious work—consequently, they’re looking for serious, high-achieving students who will positively enhance their dynamic. Additionally, these positions typically require a longer time commitment, with students working full-time (or close to full-time) hours for several months or even years. As such, accepting one of these positions may limit the other types of summer opportunities that you can participate in. Finally, due to safety concerns and restrictions, you will likely need to be at least 16 years old to participate in many types of lab-based research.

On the flip side are research opportunities that you pay to be involved in, with some being more selective than others. Many families wonder if these programs offer legitimate research experience or are simply another way to capitalize off of the college admissions craze, and the answer is that you have to do your homework.

Although some research opportunities offer little in the way of experience, others are truly authentic opportunities to work with a mentor and delve into an area of interest for academic enrichment—no different than any other cost-based summer program. In these cases, the fact that a student prioritized their intellectual curiosity and spent several months seriously pursuing a topic of interest will be an excellent addition to their application. We’ve gone ahead and done the hard work for you—any one of the opportunities listed below is legitimate and worthy of investing your time and resources into.

How do I decide what types of research opportunities to apply for?

If conducting research is important to you, we recommend applying to a mix of highly selective and lesser selective programs to maximize your chances of being accepted to at least one. Beyond selectivity, it’s important to consider additional several factors:

  • Time commitment —Some programs may require a multi-week, full-time commitment over the summer. Others may require nights and weekends during the school year.
  • Time frame —Some programs are only available in the summer while others run year-round (sometimes for multiple years).
  • Cost/stipend —Do you have to pay for the program, or does the program pay you? Research whether the program will be a good fit for your financial situation, including how much it costs and if you’ll receive compensation for your work, either via academic credit or a paycheck. Note that many residential programs are cost-based while commuter programs that only accept local students are more likely to be fully funded and/or offer a stipend.
  • Location —Evaluate whether you’d like to attend a local program, are willing to travel to a residential program, or would prefer a virtual option.
  • Level of mentor interaction —During some programs, you’ll be closely supported by PhD faculty members, while others may be run by graduate or postdoc students and require students to be more independent.
  • Opportunity to publish or enter research competitions —If publishing research or submitting your project/paper to a research competition is important to you, you’ll want to look into whether the program prepares you for that venture.

Our list includes a bevy of summer program choices as well as year-long internships and apprenticeships. We’ve divided the list into three sections: Virtual, Residential/Multi-Location, and Location-Specific.

For each entry, we list the geographic location of the program, the time frame and length of the program, any associated costs or stipends, and the eligibility criteria for participation.

Virtual Research Opportunities for High School Students

Virtual research opportunities for high school students offer ultimate flexibility, in regard to time commitment as well as subject matter.

1) Polygence

  • Location : Virtual
  • Timeframe : Academic year and/or summer
  • Length: 2-6 months
  • Cost : $495-$3,695
  • Eligibility: No age restrictions

For high school students who want to showcase authentic passion on their college applications, Polygence offers the most personalized and flexible online research program that helps students turn their interests into unique research projects. Accordingly, they pair intellectually curious students with PhD-level mentors to design experiments, build robots, create podcasts, write original screenplays, and publish in peer-reviewed journals in all fields from the humanities to STEM. All 1:1 programs include ten meetings with a mentor in your chosen field as well as a self-selected project topic and outcome, which could include a research paper, a prototype, or a creative piece of work.

A multitude of personalized options are available, including additional brainstorming sessions, time with a specialist who will guide the student through the publishing or research competition process, and academic credit through UCI x GATI. Moreover, Polygence’s Pods program allows students to work with like-minded peers in a group setting.

Sound like a good fit? College Transitions readers can save $50 on their Polygence package.

Research areas available include:

  • Computer science, engineering, AI, & game design
  • Biology, biotech, chemistry, neuroscience, and physics
  • Medicine, surgery, dentistry, and public health
  • Business, finance, and economics
  • Math, statistics, sports analytics, and quantitative analysis
  • Psychology, psychiatry, cognitive science, and social sciences
  • Creative writing, history, philosophy, and literature
  • Animation, the arts, fashion, photography, and dance

Residential/Multi-Location Research Programs

In the following section, we’ve outlined programs that are residential or offer opportunities in multiple locations, making them more accessible to a wider array of students.

Programs are organized alphabetically by discipline.

Biology Research Opportunities for High School Students

2) university of chicago research in the biological sciences (ribs).

  • Location : Chicago, IL
  • Timeframe : Summer
  • Length: 4 weeks
  • Cost : $14,000
  • Eligibility: Current sophomores and juniors

In UChicago’s highly selective RIBS program, students practice a range of molecular, microbiological, and cell biological research techniques. The goal? To prepare them to work in a research laboratory. Accordingly, for the first two weeks, students undergo basic training in lab skills and techniques. Then, they spend the final two weeks of the course immersed in an independent research project. At the end of the course, they present the project during a research forum. Moreover, students can expect weekly writing assignments and seminars. To be competitive, students should have a demonstrated interest in science as well as top grades in those classes.

Biomedical Research Programs for High School Students

3) rosetta institute of biomedical research molecular medicine workshops.

  • Location : Berkeley; San Diego; Columbia; London; virtual
  • Length: 2 weeks
  • Cost : $3,580-$4,180 (residential); $2,280-$2,480 (commuter); $430-1,050 (online)
  • Eligibility: High school students aged 14-18

Curious about biomedical research but not ready to pursue a full-blown lab internship? Rosetta Institute offers a number of residential and online two-week programs that introduce high schoolers to topics in medicine, drug development, pharmacy, and nursing. For example, current workshops include Medicinal Chemistry, Neurological Bioinformatics, and Molecular Biology of Cancer. All students are taught by PhD-level instructors and complete an original research project.

Chemistry Research Opportunities for High School Students

4) american chemical society — project seed.

  • Location : Multiple
  • Length: 8-10 weeks
  • Cost : Free, and students receive a $4,000 stipend
  • Eligibility: All high school students whose families meet annual income requirements, but preferably current sophomores, juniors, or seniors

Having been operational for more than fifty years, Project SEED (Summer Experiences for the Economically Disadvantaged) runs programs at over 350 institutions and has served over 12,000 students. The goal of the program is to empower a diverse cohort of high school students to conduct hands-on research experience in the chemical sciences. Accordingly, all students work full-time on meaningful independent or small group projects, are closely guided by a mentor, and either write a report or do a poster presentation at the end of their fellowship.

Genetics Research Opportunities for High School Students

5) jackson lab summer student program.

  • Location : Bar Harbor, ME or Farmington, CT
  • Length: 10 weeks
  • Cost : Free, and students receive a $6,500 stipend plus funded room, board, and travel
  • Eligibility: High school seniors can apply to the Bar Harbor program, while eligible undergrads can apply to either program.

Hoping to design and execute an original independent research project? You’ll be able to do just that through Jackson Lab’s Summer Student Program, which immerses students in one of seven areas: bioinformatics and computational biology, cancer, developmental biology and aging, genomics, immunology and infectious disease, metabolic diseases, and neurobiology and sensory deficits. Moreover, students are closely guided by a mentor and present their research at the end of the summer. Finally, the application process is intense and competitive, requiring two letters of recommendation, a transcript, a resume, evidence of a strong interest in genetics and genomics, and four essay responses.

Pre-Health Research Opportunities for High School Students

6) national institutes of health high school summer internship program.

  • Location : Research groups are available at many of NIH’s 27 institutes and centers , including the main campus in Bethesda, MD
  • Cost : Free; all students receive a stipend
  • Eligibility: High school seniors age 17+

Through their HS-SIP Program, the National Institutes of Health places high school students in full-time research positions within their many active research groups. Subject areas include biomedical, behavioral, and social sciences, and are geared toward students who are interested in pursuing research and healthcare. Moreover, students can take part in Summer Poster Day, where they present their research to the NIH community. They also have access to professional development programs and educational/career advising.

Note that this research opportunity for high school students is extremely competitive; approximately 7% of applicants are ultimately accepted. Finally, if you are under the age of 18 when you participate in the program, you will need to live within 40 miles of the campus that you’d like to intern at.

STEM/Humanities Research Opportunities for High School Students

7) army educational outreach program—high school internships.

  • Location : Various
  • Timeframe : All Year
  • Length: 3 months
  • Cost : Free, and all interns receive a stipend
  • Eligibility: All current high school students. Some sites may have additional eligibility requirements.

With programs currently available in twenty states, the Army Educational Outreach Program places high school students in university research labs or at a US Army Research Laboratory/Center. Each site has its own technical focus, from biology and materials science to cybersecurity and AI. Regardless of specialty, all interns receive formal mentorship from a professional scientist or engineer, have access to high-tech equipment, and work on relevant research that addresses a current major challenge.

8) Boston University RISE

  • Location : Boston, MA
  • Length: 6 weeks
  • Cost : $5,350 plus room & board
  • Eligibility: Current high school juniors

A residential program located on the Boston University campus, RISE offers high school students the opportunity to conduct laboratory research in one of two tracks: Internship or Practicum. Students in the Internship track work full-time on a research project that aligns with their interests, and are mentored by a faculty member, postdoc fellow, or grad student. 15 subject areas are available, including astronomy, mechanical engineering, medical laboratory research, and nutrition. Alternatively, Practicum students work in small groups on structured research related to systems neuroscience and neurobiology.

Research Opportunities for High School Students—Continued

9) michigan state high school honors science, math and engineering program.

  • Location : East Lansing, MI
  • Length: 7 weeks
  • Cost : $4,000

HSHSP is a highly selective, residential program where students can pursue research opportunities in science, engineering, and mathematics. After learning more about the research process, students deeply explore a problem of interest while engaging in an authentic (not “fail-proof”) research experience. Along the way, they’ll work with professionals and peers in their field of interest. Finally, many students have gone on to publish their work or be recognized at prestigious research competitions.

10) MIT Research Science Institute

  • Location : Cambridge, MA
  • Cost : Free
  • Eligibility: High school juniors

With a combined focus on academic coursework and hands-on research, RSI students first take one week of STEM coursework with MIT professors. Here, they’ll learn about current research topics in biology, chemistry, engineering, mathematics, physics, and the humanities. Then, for the remaining five weeks, students “experience the entire research cycle start to finish.” During this time, they participate in an intensive, mentored individual project experience that culminates in a written and oral presentation.

The program looks for students who are exceptionally academically talented. As such, the application process is quite intensive. PSAT Math scores must be over 740 and ACT Math scores must be over 33. In addition, students must write several essays, acquire teacher recommendations, and provide transcripts. Ultimately, only 100 students are accepted.

11) NASA Internship Programs

  • Location : Various; there are 15 centers and facilities in the US. Remote opportunities may also be available.
  • Timeframe : Available during the fall, spring, and summer
  • Length: 10-16 weeks, depending on session
  • Cost : Free; the majority of interns receive a stipend, but some are unpaid
  • Eligibility: High school students aged 16+

NASA’s Office of STEM Engagement (OSTEM) offers a number of internship opportunities for high school students. Available projects change each year and are location-specific, and not every NASA center will offer internship opportunities every session. That said, current projects span a range of subject areas, including Climate Change in the Hudson Estuary and Characterizing the Urban Land Surface Temperature. During the research internship, students will be closely mentored by a research scientist, engineer, or other professional. Note that you will need to make your own housing arrangements if you are not a local student.

Are you an undergraduate student? Check out NASA Pathways , which can provide a direct transition into full-time employment at NASA.

12) Smith College Summer Science and Engineering Program

  • Location : Northampton, MA
  • Length: 2-4 weeks
  • Cost : $4,745 (2 weeks); $8,082 (4 weeks)
  • Eligibility: Female high school students in grades 9-12; some programs have specific prerequisites

Fun fact: Smith was the first women’s college to create a program in engineering science. As such, their summer programs are an excellent place for young women to participate in hands-on, introductory research experiences. Two-week sessions are offered, and students can take one or both. Each session offers six distinct course choices. For example, the first session offers Chemistry of Herbal Medicine, Designing Intelligent Robots, and Novel Bacteriophage Discovery. Second session courses include Where the Body Meets the Mind, Supercontinents, Rocks, and Fossils, and the Art and Science of Microcontrollers. Students spend five days a week in class, attending lectures and conducting experiments & fieldwork. Additionally, the program is team-based, allowing students to learn from each other’s ideas and perspectives.

13) Stony Brook University Garcia Center Research Experience for High School Students

  • Location : Stony Brook, NY
  • Timeframe : Summer (with possible academic year continuation)
  • Cost : $4,000 plus room & board

At the Garcia Center for Polymers at Engineered Interfaces, high school students can design an original research project in polymer science and technology during an intensive seven-week summer program. Uniquely, the research can then be continued during the academic year under the guidance of a faculty mentor. Students should be highly motivated and high-achieving, with at least three upper-level science courses under their belt. Finally, past participants have regularly published their research and won recognition in national competitions.

14) Stony Brook University Simons Summer Research Program

  • Cost : Students need to cover transportation costs (if commuting) or room/board (if residential). Room/board is $2,781. Stipends are also awarded at the end of the program.

After being matched with a mentor and research team, students are fully immersed in the research process. Placement availability varies from year to year, but typically about thirty projects are available across over a dozen disciplines. These include biochemistry, computer science, geosciences, and pharmacological sciences, among others. Moreover, some have prerequisites, such as specific AP courses or previous programming experience.

All students participate in weekly faculty research talks, workshops, events, and a culminating poster symposium.

15) Summer Science Program

  • Location : Astrophysics: UNC Chapel Hill, University of Colorado, Georgia College & State University, New Mexico State University; Biochemistry: Purdue, Indiana University; Genomics: Georgetown, Purdue, New Mexico State; Synthetic Chemistry : Southwestern Oklahoma State University
  • Cost : $8,800 max; all program fees are scaled according to what each family can afford
  • Eligibility: Current high school juniors and exceptional sophomores

The Summer Science Program offers four different immersive research programs that take place on different college campuses around the country. These include programs in astrophysics, biochemistry, genomics, and synthetic chemistry. Each program has its own research focus. For example, astrophysics students will dive into Asteroid Orbit Determination while genomics students explore Antibiotic Resistance and Directed Evolution.

Students spend six days a week in class deeply investigating their research topics and learning more about general experimental science. They also take part in guest lectures and other special programming.

16) Texas Tech University Anson L. Clark Scholars Program

  • Location : Lubbock, TX
  • Cost : Free; all students receive a $750 stipend upon completion of their projects
  • Eligibility: High school juniors and seniors aged 17+ by the start of the program

The Clark Scholars Program is one of the only programs on this list with research disciplines in the sciences as well as the humanities. For example, current research areas include everything from nutritional sciences and mechanical engineering to history. Over the course of seven weeks, students work closely with a faculty member to complete a research paper in their discipline. They also participate in weekly seminars, discussions, and field trips.

17) University of California Santa Barbara Research Mentorship Program

  • Location : Santa Barbara, CA
  • Cost : $11,874 (residential); $4,975 (commuter)
  • Eligibility: High school sophomores and juniors

During this intensive program, students work 35-50 hours per week on an interdisciplinary research project of their choice. Nearly thirty research areas are available in both the STEM disciplines and humanities; current topics include biochemistry, computer science, history, music, and anthropology, among others. Over the course of the program, they also take two courses: Introduction to Research and Presentation Techniques. Finally, students occasionally continue their research remotely during the academic year, depending on their mentor’s availability.

18) University of California Santa Barbara Summer Research Academies

  • Cost : $8,224 (residential); $2,575 (commuter)
  • Eligibility: High school sophomores, juniors, and seniors

Running for four weeks, the UCSB Summer Research Academies allow students to earn up to four credits. While taking a university-level course that teaches fundamental research concepts, students spend the first two weeks of the program developing a research question & framework via hands-on labs. They’ll then spend the final two weeks of the course analyzing their results and building presentations. Overall, they’ll spend about 25-40 hours per week working. Finally, twelve different tracks are available; each involves multiple disciplines. For example, “Bionic Creatures” combines mechanical engineering, materials science, soft robotics, biomanufacturing, and collective motion.

19) University of California Santa Cruz Science Internship Program (SIP)

  • Location : Santa Cruz, CA
  • Length: 9 weeks (two weeks virtual, seven weeks in-person)
  • Cost : $4,750 plus room & board
  • Eligibility: High school students aged 14+, although some research groups require students to be 16+

UCSC’s SIP Program offers a wide range of research focus areas, including science and engineering as well as social science, humanities, and art. For example, over 100 projects are currently offered that include everything from “Eating Insects in Silicon Valley: Cultural Gaps Between Food-Tech and Tradition” and “Future Projected Changes in the Distribution and Variability of Ocean Chlorophyll in Climate Simulations.” Before you dive in, you’ll spend two weeks doing online research prep (this part is conducted remotely) followed by seven weeks of in-person, mentored research. Students get to engage in authentic, open-ended projects that fully immerse them in the academic research experience. Moreover, they’ll present their findings at a symposium at the end of the program.

20) University of California Davis Young Scholars Program

  • Location : Davis, CA
  • Cost : $6,750
  • Eligibility: High school sophomores and juniors who will be 16+ by the start of the program

Interested in biological, agricultural, environmental, or natural sciences? If so, UC Davis is a stellar place to explore those interests through research. All students have the opportunity to work on independent, original projects while receiving one-on-one faculty mentorship. Moreover, they each produce a journal-quality paper and symposium presentation. In addition to research, students also participate in a lecture series presented by UC Davis faculty; past topics have included forensic entomology and nutrition, among others. Finally, field trips to educational facilities like the Monterey Bay Aquarium and Bodega Bay Marine Laboratory round out the experience.

21) University of Florida Student Science Training Program

  • Location : Gainesville, FL
  • Cost : $5,200
  • Eligibility: Rising seniors aged 16+

Thinking about a career in science, medicine, math, computer science, or engineering? UF’s Student Science Training Program could be the right fit. For thirty hours per week, you’ll work with a faculty mentor and lab team on university-level, ongoing research. Moreover, you’ll participate in a science lecture series as well as a UF Honors Program seminar class. Over the course of the program, you will write a research paper, present a poster, and give two oral presentations. Finally, social programming is included.

22) University of Iowa Secondary Student Training Program

  • Location : Iowa City, IA
  • Cost : $7,500

During this intensive and competitive program, students conduct research within small groups that are supported by a University of Iowa faculty member. There are twenty current active research areas, including chemistry, geography, neurology, orthopedics & rehabilitation, and religious studies. You’ll be working on your project approximately seven hours per day, attending classes in the evenings, and participating in structured activities on the weekend. Moreover, all groups will create and present a poster at the culmination of the program.

23) University of Massachusetts Amherst Summer Programs

  • Location : Amherst, MA
  • Cost : $3,636 (residential); $2,167 (commuter)
  • Eligibility: Rising sophomores, juniors, and seniors

UMass Amherst offers two introductory, research-focused opportunities for high school students. These are Antibiotic Resistance: A Global Health Crisis, which allows students to join the Department of Microbiology in researching new antibiotics, and Energy Without Borders, which delves into climate change, infrastructure, and green energy. In both courses, you’ll learn research methods, complete multiple lab experiences, and present a research poster. Finally, students can earn two college credits upon successful completion of the program.

Location-Specific Research Opportunities for High School Students

The following programs are not residential and only offered in a specific location. Many also only accept local students, although some do allow out-of-state students to apply. If that’s the case, you will need to secure your own living accommodations and transportation. Moreover, if you are under the age of 18, you will need to be supervised by a parent or guardian.

Programs are organized alphabetically by state.

24) California Academy of the Sciences—Careers in Science Intern

  • Location : San Francisco, CA
  • Focus: STEM
  • Length: Multi-year (2-3 years)
  • Eligibility: 9 th or 10 th grade student enrolled in an SFUSD school with a GPA of 2.5 or higher

25) Cedars Sinai INSPIRE High School

  • Location : Los Angeles, CA
  • Focus: Pre-Health
  • Cost : Free; all students are paid
  • Eligibility: High school students age 16+

26) City of Hope Summer Student Academy

  • Location : Duarte, CA
  • Focus: Biomedicine
  • Cost : Free; all students receive a stipend of $4,000

27) Sandia National Laboratories—Internships

  • Location : Livermore, CA
  • Focus : STEM
  • Timeframe : Academic year and summer internships available
  • Length: Academic year or 10-12 weeks (summer)
  • Cost : Free; all positions are paid

28) Scripps Student Research Internship Program

  • Location : La Jolla, CA
  • Focus : Translational science/genomics
  • Cost : Free; stipends are typically offered

29) UCSF SEP High School Intern Program

  • Focus : Biomedical research
  • Length: 8 weeks
  • Eligibility: High school juniors enrolled in an SFUSD high school, SF charter school, or College Track San Francisco

30) UCSF Summer Student Research Program

  • Location : Oakland, CA
  • Length: 9 weeks
  • Cost : Free; all students are given a stipend between $3,000-$4,300
  • Eligibility: High school juniors or seniors, aged 16+

Connecticut

31) jackson lab academic year fellowships.

  • Location : Farmington, CT*
  • Focus: Genetics
  • Timeframe : Academic year
  • Length: 1 school year
  • Cost : Free; students must be able to receive academic credit for their work
  • Eligibility: High school juniors and seniors age 16+ within commuting distance of the lab

*Some fully remote opportunities are available

32) Yale School of Medicine Discovery to Cure High School Internship

  • Location : New Haven, CT

33) Yale University Social Robotics Lab High School Internship

  • Focus: Robotics and human social behavior
  • Eligibility: Rising juniors and seniors aged 16+

34) Argonne National Laboratory — Exemplary Student Research Program

  • Location : Lemont, IL
  • Focus: Engineering
  • Eligibility: Application must be completed by participating teacher

35) Chicago EYES on Cancer

  • Focus : Biomedicine
  • Timeframe : All year, with two 8-week summer research experiences
  • Length: 2 years
  • Cost : Free; all students receive $3,100 stipend
  • Eligibility: High school sophomore, junior, or senior aged 16+

36) University of Kansas Biotech Research Apprentice Program

  • Location : Overland Park, KS
  • Focus : Biotech
  • Length: Semester

37) Jackson Lab Academic Year Fellowships

  • Location : Bar Harbor, ME*

38) National Cancer Institute Werner H. Kirsten Student Internship Program

  • Location : Frederick, MD
  • Timeframe : Academic year & summer
  • Length: 1 year
  • Cost : Free; academic credit available during school year, stipend provided in summer
  • Eligibility: High school junior age 17+ who attends an eligible school located within a 30-mile radius of campus

39) University of Minnesota Lillehei Heart Institute Summer Research Scholars Program

  • Location : Minneapolis, MN
  • Focus: Cardiovascular medicine
  • Eligibility: High school juniors and seniors age 16+ as well as undergraduate students

40) Coriell Institute for Medical Research

  • Location : Camden, NJ
  • Eligibility: High school student aged 17+

41) Princeton Laboratory Learning Program

  • Location : Princeton, NJ
  • Focus : Natural Sciences or Engineering
  • Length: 5-6 weeks

42) Princeton Plasma Physics Laboratory High School Internship

  • Location : Princeton, NJ*
  • Focus : Physics
  • Eligibility: High school seniors (program takes place summer after graduation)

*Remote projects may be available.

43) Rutgers Institute for Translational Medicine and Science Summer Research Program (RITMS)

  • Location : Rutgers, NJ
  • Focus : Translational medicine/science

44) Rutgers Waksman Institute Summer Experience Program

  • Location : Piscataway, NJ*
  • Focus : Molecular biology/bioinformatics
  • Cost : $2,000
  • Eligibility: High school students who have completed a high school-level biology course

*Online version of the program is also available

45) Los Alamos National Laboratory High School Internship Program

  • Location : Los Alamos, NM
  • Length: 11 weeks
  • Eligibility: New Mexico high school seniors aged 16+

46) Sandia National Laboratories—Internships

  • Location : Albuquerque, NM

47) Baruch College STEM Research Academy

  • Location : New York, NY
  • Timeframe : Spring/summer
  • Cost : Free, but all students receive a stipend of $1,575
  • Eligibility: Must be a NYC public high school sophomore junior to apply

48) Burke Neurological Institute NeuroAcademy

  • Location : White Plains, NY
  • Focus: Neuroscience
  • Eligibility: Completion of NYS Regents Living Environment or equivalent Biology class; cumulative GPA of 3.4 or higher

49) City Tech College STEM Research Academy

  • Length: Two semesters (January-August)
  • Eligibility: NYC public school sophomore or junior

50) Columbia Zuckerman Institute—BRAINYAC Program

  • Eligibility: High school sophomores and juniors from select partner programs/schools in Upper Manhattan and the Bronx

51) HOPP Summer Student Program at Memorial Sloan Kettering Cancer Center

  • Focus: Biomedical or computational research
  • Eligibility: High school students aged 14+

52) University of Rochester Laboratory for Laser Energetics Summer High School Research Program

  • Location : Rochester, NY
  • Focus: Laser energetics
  • Eligibility: Rochester-area high school students who have completed their junior year

53) Cleveland Clinic Lerner Research Institute

  • Location : Cleveland, OH
  • Timeframe : Varies; depends on lab
  • Length: Varies; depends on lab

54) OHSU School of Medicine Partnership for Scientific Inquiry (PSI)

  • Location : Portland, OR
  • Focus: Biomedical research
  • Timeframe : Academic semester + summer
  • Length: 16+ weeks
  • Eligibility: Oregon-based high school sophomores, juniors, and seniors aged 16+

Pennsylvania

55) fox chase cancer center high school research programs.

  • Location : Philadelphia, PA
  • Timeframe : During school year
  • Length: 2-3 months; depends on program
  • Eligibility: Philadelphia-area high school students; students must be 16+ for some programs

56) Penn State College of Medicine Research Internships

  • Location : Hershey, PA
  • Length: Varies; could be weeks to months depending on lab
  • Cost : Paid and unpaid internships available

57) University of Pennsylvania GRASP Lab High School Internships

  • Focus: Robotics
  • Cost : Free; stipend typically available
  • Eligibility: Rising high school senior

58) George Mason University Aspiring Scientists Internship Program (ASSIP)

  • Location : Fairfax, VA*
  • Eligibility: High school students aged 15+ or 16+, depending on program

*Some fully remote and hybrid opportunities are available, depending on the lab.

59) Jefferson Lab High School Summer Honors Program

  • Location : Newport News, VA
  • Eligibility: High school students aged 16+ who live within 60 miles of the lab

60) Virginia Tech Fralin Biomedical Research Institute Summer Research Program

  • Location : Roanoke, VA
  • Focus: Health behaviors research
  • Cost : Free; all students receive a stipend of $4,800
  • Eligibility: Rising high school junior or senior in the Roanoke Valley

61) Pacific Northwest National Laboratory High School Research Programs

  • Location : Richland, WA
  • Timeframe : Summer & academic year programs available
  • Length: Academic year or 10 weeks (summer)
  • Eligibility: High school students aged 16+; some labs may require students to be 18+

62) Seattle Children’s Hospital Research Training Program

  • Location : Seattle, WA
  • Eligibility: High school sophomores, juniors, or seniors within commuting distance of downtown Seattle

Final Thoughts—Research Opportunities for High School Students

If gaining research experience is important to you, it’s in your best interest to explore a number of different programs, evaluating whether their structure, length, cost, and outcomes are in line with your goals. Finding the right opportunity may take some time, but it will be well worth the effort required.

  • Research Programs

Kelsea Conlin

Kelsea holds a BA in English with a concentration in Creative Writing from Tufts University, a graduate certificate in College Counseling from UCLA, and an MA in Teaching Writing from Johns Hopkins University. Her short fiction is forthcoming in Chautauqua .

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Extracurriculars.

how to do medical research in high school

Extracurriculars for High Schoolers Interested in Studying Medicine

If you have your sights set on a career in medicine, you probably already know that the field is selective and fast-paced. Spots in the top BS/MD programs in the country are among the most competitive to land, and even top pre-med programs often have acceptance rates in the single digits. 

For students aiming for a medical career, top grades and test scores aren’t enough to get into the best programs in the country. Grades and test scores might be great examples of your scholastic aptitude, but they don’t reveal much about your personal characteristics. Do you help your community and those around you? Do you commit fully to tasks? Do you solve problems in innovative, insightful ways? 

Qualities like dedication, empathy, and leadership are critical to success in medical school and in a medical career, so admissions committees look for these traits in applicants. You’ll need to use your extracurricular involvement to let these qualities shine through if you want to set yourself apart in the admissions process. This post will help you think creatively about how to select a range of clubs, activities, and competitions to demonstrate your interest in medicine. Read on to learn more. 

The Four Tiers of Extracurricular Activities

Before diving into specific extracurricular options for students interested in medicine, let’s talk about how admissions committees typically view different extracurriculars. 

You probably already know that some extracurriculars are more impressive than others. Factors like the duration of your participation and your level of involvement influence how the admissions committee will view each item on your activities list. When weighing the importance and value of an extracurricular on a college application, we at CollegeVine like to divide activities into four tiers . These tiers can help you understand how your extracurricular profile will stack up against that of other applicants. 

Tier one activities are the most impactful—and the most rare. They demonstrate exceptional achievements and high-level leadership. Examples include winning the Google Science Fair, attending a prestigious top summer program like the PROMYS program at Brown University , or ranking nationally as an athletic recruit. More unconventional activities that show extraordinary initiative—like starting a highly successful service organization or business—can also reach tier one status. Few students have tier one level accomplishments, so those who do automatically stand out. 

Tier two activities are slightly less extraordinary than tier one activities, but they are still impressive. These activities typically show a high level of achievement or leadership. Tier two activities might include serving as the president of your school’s Model UN chapter, winning a regional debate competition, or earning a place in the all-state orchestra. Tier two activities are still a powerful addition to your college application, though they won’t be as instantly eye-catching for admissions officers as tier one activities. 

Tier three activities are fairly common, though they still show specific commitment and accomplishment. This category of activities include being recognized as player of the week on your soccer team, serving as secretary of your school’s french club, or winning your school’s science fair. 

Finally, tier four activities are those activities that are very common and so will likely not make your college application stand out. Tier four activities are typically activities that you participate in without achieving a leadership role or particular distinction. While these activities aren’t especially impressive, they can still demonstrate your interests and experience. 

This tier system can be applied to all extracurricular activities; the appropriate mix of tiers will vary depending on your college goals. If you’re applying to highly competitive programs, like BS/MD or pre-med programs, you’ll need the strongest extracurricular profile possible; this means that you should aim to move your extracurriculars “up” to higher tiers throughout high school. Below, we’ll cover which specific extracurriculars you might want to consider if your goal is to go into medicine.

If you want to learn more about our tier breakdown system, check out this post.

how to do medical research in high school

Extracurriculars to Consider if You Intend to Study Medicine 

Though your level of involvement in an activity plays significantly influences its impact on your application, the kinds of activities you choose are also very important. As we mentioned above, if you’re interested in medicine, you should choose extracurriculars that showcase your skills in the sciences and your commitment to pursuing medicine. Below, we provide a list of clubs and activities to get you started as you consider how to achieve this goal.

Interest-based clubs. This classic extracurricular option allows students to learn and collaborate with peers who share their interests. Here are some interest-based clubs that could be a good fit if you’re interested in studying medicine:

  • Anatomy Club
  • Biology Club
  • Medical Explorers
  • Neuroscience Club
  • Pre-Med Club
  • Sports Medicine Club
  • This international organization provides medical professionals with the opportunity to volunteer in high-need communities around the world. High school Doctors Without Borders clubs typically raise awareness and funds to support Doctors Without Borders’ mission. By getting involved with this organization and taking on a leadership role, you can show your empathy and dedication to helping others. 
  • This national organization provides pre-professional guidance to high schoolers who are interested in becoming doctors, nurses, or pursuing other healthcare-related careers. HOSA organizations offer students an unusual opportunity to simultaneously learn about medical careers and show off their knowledge in HOSA’s competitions. 

This list shows the variety of interest-based, medicine-relevant extracurriculars that might be available to you. As you consider your options, think creatively and choose a menu of activities that both appeal to you and give you an opportunity for leadership and achievement. And keep our tier system in mind: If you commit to your extracurriculars and take on leadership roles,  you’ll gain valuable experience and boost your extracurricular profile. 

Competitions. Beyond interest-based extracurriculars, academic competitions can show off your preparation for pre-med (and eventually medical!) studies. The HOSA – Future Health Professionals competitions offer one opportunity to display your medicine-specific knowledge. 

More generally, you might consider participating in the Biology Olympiad , the premier national biology competition for high schoolers, sponsored by the Center for Excellence in Education. 20 finalists, selected through two rounds of written exams, attend a residential training program; from those 20, four finalists are selected to represent the United States at the International Biology Olympiad. 

Remember: In academic competitions, the path to impress admissions committees is relatively narrow. Merely participating in a competition like the Biology Olympiad could show your enthusiasm for biology, but, within the framework of our tier system, would only register as a tier four achievement. Higher levels of success would bring more strength to your application: A top placement could really catch admissions committees’ attention, and would be a tier one achievement; doing significantly better than the average participant could be a tier two or three achievement. 

Internship, shadowing, and research. Medicine differs from many other science-based disciplines because of its applied dimensions. From conducting research to interacting with patients, students in medical school and doctors have to apply their knowledge in unique ways. 

High school students can gain exposure this sort of hands-on experience by shadowing a local doctor, interning at a hospital or doctor’s office, or conducting relevant research. These activities, though not traditional extracurriculars, can show that you understand the day-to-day realities of a medical career–and that you’re eager to take on its challenges. Showing that you understand the challenges of medical school (and medicine!) is important for pre-med applicants, and especially important for BS/MD applicants. In fact, many BS/MD programs require or strongly encourage applicants to have research, internship, or shadowing experience! 

For more ideas, check out these awesome CollegeVine posts:

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  • Your Ultimate Guide to Summer Programs for High Schoolers
  • 15 Medical Internships for High School Students

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Everything You Need to Know About Starting Out With Research in High School

If you are passionate about a certain subject, doing research in that field is a fantastic way to explore your interests, set the building blocks for a future career, and stand out on college applications. However, for many students, the idea of conducting research seems daunting and inaccessible while in high school and the question of where to start remains a mystery. This guide’s goal is to provide a starter for any students interested in high school research.

Research experience for high school students: Why do research?

Research is a fantastic way to delve into a field of interest. Research students at Lumiere have investigated everything, from ways to detect ocean health, new machine learning algorithms, and the artists of the 19th century. Engaging in research means you can familiarize yourself with a professional environment and develop high-level research skills early on; working with experts means you might discover things you may have never dreamed of before. You are given a valuable opportunity to think ahead and ask yourself foundational questions:

“Is this what I want in a future career?”

“What do I like and dislike about this process?”

As a huge plus (and do not underestimate the value of this!), you will likely gain extremely valuable connections, mentors, and recommenders in working closely with your team.

Let’s face it, the college selection process is becoming more and more competitive each year and admission teams are always looking for new ways to distinguish strong candidates. Doing a research project shows that you are someone with passions and, more importantly, someone with a willingness to take the extra step and explore those passions. You showcase your abilities, ambition, work ethic, eagerness to learn, and professionalism, all at the same time. This will no doubt help you when the time for college applications rolls around.

How to do research in high school: finding opportunities

Now that we’ve covered the ‘why’, let’s cover the ‘how’! There are two ways you can go about this, and it’s a great idea to run these in parallel so that one can serve as a backup for the other.

1. Identify research opportunities and apply strategically: Some opportunities are recurring programs. Usually, these are advertised. These can be structured research programs or internships run by universities, non-profits or government departments.

Organization and preparation were key to my own application processes, so be sure to start thinking ahead. Note that most research programs take place in the summer and require applications that are due by January or February. Make a spreadsheet of programs you’d be interested in and take note of their application deadlines, cost, required materials, etc. Applications often have you write essays and submit recommendation letters, so you want to think about those in advance as well.

2. Cold email to find research opportunities that are not advertised: Another way to pursue research outside of the programs is to try contacting people directly and get involved in their research projects. This would mainly involve university faculty, but you might also find a mentor elsewhere; for instance, if you are interested in medical work, you could contact someone at your local hospital. If you are interested in government, you might reach out to your local representative. If you don’t have any personal connections with faculty members in your field, cold emailing them is the way to go. You’ll need to email a lot of researchers; chances are some are busy, some aren’t in need of interns, and some simply don’t check their emails. To up your chances, you should try reaching out to at least 25 people of interest.

For cold emailing, you’ll be asking for opportunities that may not be advertised. You’ll need to prepare an “email template” of sorts that you’ll be sending out to everyone. It should start with an introduction—who are you, where are you from, how do you know this person—and include a set of your skills and interests that you could bring to the table. Keep this email short, friendly and to the point. Don’t be afraid to follow-up if they don’t respond within the first two weeks! Your message might have just gotten lost in their inbox. You’ll also want to update your resumé to attach to the email be sure to include any relevant coursework, accomplishments, and experience in the field.

Types of research opportunities for high school students

1. do a structured research program in high school.

Structured research programs are excellent ways to gain experience under some top researchers and university faculty, and often include stays at actual labs or college campuses with a wide variety of peers, mentors, and faculty. Examples of some competitive research programs include Research Science Institute (RSI) hosted by MIT, the Summer Academy for Math and Science (SAMS) offered by Carnegie Mellon, and a program hosted by the Baker Institute at Rice University for students interested in political science. For more options, here’s a list of 24 programs for this upcoming summer that we’ve compiled for you!

Another great way of deep-diving into an area of your interest and doing university-level research is through 1-1 mentorship.

Lumiere Research Scholar Program

Founded by Harvard and Oxford researchers, Lumiere offers its own structured research programs in which ambitious high school students work 1-1 with top PhDs and develop and independent research paper.

Students have had the opportunity to work on customized research projects across STEM, social sciences, AI and business. Lumiere’s growing network of mentors currently has over 700, carefully selected PhDs from top universities who are passionate about leading the next generation of researchers. The program is fully virtual! You can find the application form here .

Also check out the Lumiere Research inclusion Foundation , a non-profit research program for talented, low-income students.

Veritas AI’s Summer Fellowship Program

Veritas AI has a range of AI programs for ambitious high school students , starting from close-group, collaborative learning to customized project pathways with 1:1 mentorship . The programs have been designed and run by Harvard graduate students & alumni.

In the AI Fellowship, you will create a novel AI project independently with the support of a mentor over 12-15 weeks. Examples of past projects can be found here .

Apply now !

2. Work with a professor in high school

Research typically asks for an advisor, professional, or mentor. So how does someone end up doing research with a researcher in high school? The very first thing you need to do is identify an area of interest. If you really enjoy biology at school, perfect. If you find history fascinating, you’ve found your topic. The important thing is that you’re truly interested in this area; any discipline is fair game!

3. Participate in competitions and fairs

There are many research competitions and fairs available for high school students to participate in. For example, the Davidson Institute offers cash scholarships for student projects in science, technology, engineering, mathematics, literature, music, or philosophy. The Regeneron International Science and Engineering Fair is a particularly well-known competition for students who have completed independent research projects. Research fairs are a great way to motivate students in pursuing their own interests, showing initiative and drive. Winning a competition also looks great on a resumé! Check out Lumiere’s guide to research competitions here .

4. Pursue your own passion projects

A passion project can mean more than just a presentation made for competition. For example, a student I know created an app to track music trends at our school and then analyzed the data on his own—just for fun! It was a great story to include on his future internship applications. Take a look at Lumiere’s guide for passion projects here .

5. Write a research paper

Once you’ve pursued your own research project, writing a research paper is a next great step. This way, you have a writing sample you’ll be able to send to colleges as an additional supplement, or to labs and researchers for future opportunities. It’s also a fantastic exercise in writing. We know that many high school students might struggle with learning how to write a research paper on their own. This is something you might work with your high school science teacher on, or with the guidance of a Lumiere mentor.

6. Research internships

These can be standalone or part of a research program. In looking for a more structured research experience, a research internship can be particularly valuable in building strong foundations in research. There are always tons of internship opportunities available in all different fields, some as specific as medical research . If you are wondering how to get a research internship in high school, then check out our blog posts and apply!

Things to keep in mind when working with a researcher.

You’ve gotten into a research program! Now you want to do the best job possible. There are a few things to keep in mind while conducting research.

1. Maintain a professional and friendly demeanor

Chances are, there are many things you don’t know or haven’t learned about this field. The important thing is to keep an open mind and remain eager to learn. Don’t be afraid to ask questions or to offer to help with anything, even if it’s not in your job description. Your mentor will appreciate your willingness to adapt, follow procedures, and engage with challenging material.

2. Keep track of what’s happening

Open up your notes app or get a small journal to remember what has happened in each step of the process. I remember the hardest part of writing my college essays was the very beginning: trying to come up with a list of memorable moments to talk about. If you’re looking to write about your research experience in your college application, you need to remember the moments where you struggled, where you learned, where you almost gave up but didn’t, where you realized something, even the moment you first stepped into the lab! If you are given feedback: write that down! If you are asked to reflect on everything you learned: write that down! This will be incredibly important for now and for later.

3. Ask questions

Not only is your mentor there as a potential future recommender, but they are also there to help you learn as much as possible. Absorb as much as you can from them! Ask as many questions as you can about their career, their previous research, their education, their own moments of realization, etc. This will help you discover what this career really entails and what you might look for in navigating your own future career.

Making the most out of your research: How to publish a research paper in high school

A question we often get is whether or not you need to publish your research for you to mention it in your college application. While the answer is no, the experience is a great one to have and definitely allows your work to stand out amongst your peers. Lumiere has published a complete guide to publishing research in high school here . What’s important to keep in mind is that there are various journals that specifically accept high school research reports and papers, such as the Concord Review or the Journal of Emerging Investigators. In our articles below, we go through a detailed guide of what these journals are and how a student might best approach the submission process.

Useful guides for publishing a research paper in high school

The Concord Review: The Complete Guide To Getting In (lumiere-education.com)

The John Locke Essay Competition

The Complete Guide to the Journal of Emerging Investigators (lumiere-education.com)

Research is an incredibly rewarding learning experience for everyone. While high school may seem early, it’s always better to start sooner rather than later, both for your college applications and for your own personal progress. Although the process may seem daunting at first, we hope we’ve broken it down in a way that’s simple and digestible. And if you want extra support, the Lumiere Research Scholar Program is always here to help!

Amelia is a current junior at Harvard College studying art history with a minor in economics. She’s enthusiastic about music, movies, and writing, and is excited to help Lumiere’s students as much as she can!

How to Get Research Experience

New section.

Working in a research setting can help make you a competitive medical school applicant and help you to determine if a career in medicine or medical research is right for you

how to do medical research in high school

How do I find a research position?

If you’re currently in college, check with your institution’s science or undergraduate research websites for opportunities to assist with faculty research projects. You can also review faculty bio pages and lab websites for more information. Next, reach out to your immediate network: express your interest in assisting with a research project to your science professors, academic advisor, and your pre-health advisor.

Try exchanging ideas with your peers and upper-classmen for advice on research opportunities at your institution. You can also ask peer advisors, resident advisors, or any fellow premedical students for introductions to principal investigators (PIs). You might even try the “Undergrad-Grad-PI” method. This is where you first reach out to undergraduate students in research labs to learn about their responsibilities; they oftentimes are more responsive. Then, reach out to the graduate or post-doc students to learn about the research question being investigated. After this, read the most recent paper or abstract the lab published. Once you complete these steps, you can approach the PI more confidently and more effectively demonstrate your commitment to and understanding of their project.

Your school’s career center or student employment office may know about research job openings, and they can also offer resume help and go over interview tips and techniques. Remember, opportunities may be on or off campus, full- or part-time, paid or unpaid, or part of a summer program. Once you find a position, you can connect with your school’s fellowships or awards office to inquire about research funding opportunities.

If you’ve already graduated, consider looking into open positions. Research hospitals, universities, and biotech companies are always looking for lab technicians or clinical research coordinators (CRC). Job opportunities are typically posted on the career pages of their websites.

When should I begin gaining research experience in college?

Some premedical students begin their research experiences during their first year of college, and others begin research positions after they have already graduated. On average, most students secure a research position junior or senior year. There are three big factors that will impact this:

  • Your level of interest in pursuing research. If you are really excited to investigate a question under a mentor, you might find yourself reaching out to professors early and often. Other students may focus on gaining clinical experience, and therefore wait later in their academic career to start research.
  • Readiness for the research project. Different PIs will have different expectations for preparation. A research project might require you to first take coursework in basic lab sciences, statistics, or another advanced topic specific to the project. Other PIs may prefer to train you “on-the-job” through their graduate or post-doc students. This will impact when you are ready to join a project.
  • Finding the right research project. There is a process of reviewing different PIs and research projects to find the right fit for you. What subject do you want to investigate? Do you want your research project to take place in a lab or non-lab setting? Is there an independent question you want to investigate with the help of a mentor?

When is the best time to look for a position?

According to Kate Stutz, Ph.D., Director of Pre-Health Advising at Brandeis University, if you’re interested a research position during the academic year, the best time to look for positions is at the very beginning of the semester. There also tend to be a lot of research opportunities in the summer, both paid and volunteer, through set programs like the National Science Foundation’s Research Experience for Undergraduates (REUs). It’s best to start applying for summer research positions in December-February for the upcoming summer. Remember, typically there are more applicants than available spots so get your applications in early. Each undergraduate institution will be different, therefore make sure to connect with your advisors and peers for feedback on when to start looking.

What’s the best way to apply?

The outreach email message that you send to potential research faculty is very important. This message should include a formal introduction of yourself, evidence that you are familiar with their research project(s), and a clear, specific ask. Identify what you hope to contribute to the project. Do you want to clean the glassware or analyze lab findings? Consider attaching your resume as well. Dr. Stutz stresses that networking and persistence are crucial to finding a position. Make sure you’re using all of your network, including your peers and professors, to find open positions. Don’t be afraid to send follow up emails; faculty are very busy and often overlook emails. Sometimes, it can be even more effective to stop by a professor’s office hours to hand deliver your materials and indicate your interest in person.

How should I prepare for an interview?

With any interview, it’s important to make a good impression. Be sure to dress appropriately. Come prepared with a resume. Use your campus career center for advice on proper attire and resume best practices.

Often during interviews, you’ll be asked about your career goals. It’s helpful to be able to speak about the steps you plan to take to meet those goals. Talk about classes you’ve taken, especially upper-level science courses. Speak about your skills, your knowledge of techniques, and the equipment you’ve used throughout your coursework. Be prepared to discuss the lab experiments you’ve completed. If you’ve done any sort of research—even in your coursework—keep track of it. This shows you have experience. Lastly, interviewers often ask candidates if they have any questions. Dr. Stutz suggests asking something that indicates you’ve done your own research into their project. You could ask where they see their research going in the next three years or what challenges they anticipate. You could also ask about expectations for undergraduate researchers; do they expect you to work 20+ hours a week? Full time over the summer? Do they require you to have work study or to sign up for research credits? Asking these questions ahead of time can help you plan ahead and determine if this position is the best fit for you. Check out these  interview resources  for more tips.

Does research experience have to be in a wet lab?

No! Research can be performed in any field or subject. We’ve had successful applicants with research in classics, sociology, history, and policy, as well as applicants with research in biology, biochemistry, and neuroscience. Medical schools value all types of research. Research can take place in a scientific lab that requires advanced devices and procedures to obtain data for analysis. Research can also take place in the humanities or social sciences where participant interviews or surveys are needed to obtain an individual's life perspective. The clinical research field is constantly investigating patient outcomes and how to improve care through clinical trials or analysis of patient data. As a premedical student, consider what question you want to investigate further. Do you want to learn more about how health inequities impact disadvantaged communities in your area, or perhaps you want to know more about the protein channels involved in memory cognition? Once you choose a direction, you can then partner with a research PI for guidance on how to navigate your question. Sierra Perez, Pre-Health Advisor at Brandeis University, shares not to be afraid to get creative with your research question. She has been impressed by the medical school applicants who have created independent questions that address the community needs. “Applicants are recognizing the critical needs of specific populations, such as homelessness, LGBTQ+, veterans, youth with disabilities, etc.,” she stated. “There is also a demand for translational researchers, or individuals who can take complicated bench topics and apply it to the clinical world.”

Is research experience required to be accepted to medical school? 

It depends. Some medical schools are very research focused; they may require a research thesis or have research time built into the curriculum. Other schools are more community or clinically focused; they would rather have an applicant work in a healthcare setting or volunteer at their local soup kitchen than be at the bench moving clear liquids from one test tube to another. Research experience (in whatever discipline) is helpful for developing some of the Premed Competencies , such as critical thinking, quantitative reasoning, scientific reasoning, as well as teamwork and oral communication skills. How much you should engage in research depends on how much you enjoy it once you try it!

The majority of accepted medical school applicants have some form of academic or clinical research at the time they apply. Competence in research has become increasingly important in the medical field to improve patient care outcomes.

You can also review medical school mission statements to see if research is a focus at a particular school. You can read each school’s mission, and the number of accepted students in their most recent class who had research experience, in the  Medical School Admission Requirements . Remember, it’s best to pursue experiences that you’re genuinely interested in, rather than just to check a box, but you may not know if research is for you until you give it a try.  

Medical Research

How to conduct research as a medical student, this article will address how to conduct research as a medical student, including details on different types of research, how to go about constructing an idea and other practical advice., kevin seely, oms iv.

Student Doctor Seely attends the Rocky Vista University College of Osteopathic Medicine.

In addition to good grades, test performance, and notable characteristics, it is becoming increasingly important for medical students to participate in and publish research. Residency programs appreciate seeing that applicants are interested in improving the treatment landscape of medicine through the scientific method.

Many medical students also recognize that research is important. However, not all schools emphasize student participation in research or have associations with research labs. These factors, among others, often leave students wanting to do research but unsure of how to begin. This article will address how to conduct research as a medical student, including details on different types of research, how to go about constructing an idea, and other practical advice.

Types of research commonly conducted by medical students

This is not a comprehensive list, but rather, a starting point.

Case reports and case series

Case reports are detailed reports of the clinical course of an individual patient. They usually describe an unusual or novel occurrence or provide new evidence related to a specific pathological entity and its treatment. Advantages of case reports include a relatively fast timeline and little to no need for funding. A disadvantage, though, is that these contribute the most basic and least powerful scientific evidence and provide researchers with minimal exposure to the scientific process.

Case series, on the other hand, look at multiple patients retrospectively. In addition, statistical calculations can be performed to achieve significant conclusions, rendering these studies great for medical students to complete to get a full educational experience.

Clinical research

Clinical research is the peak of evidence-based medical research. Standard study designs include case-controlled trials, cohort studies or survey-based research. Clinical research requires IRB review, strict protocols and large sample sizes, thus requiring dedicated time and often funding. These can serve as barriers for medical students wanting to conduct this type of research. Be aware that the AOA offers students funding for certain research projects; you can learn more here . This year’s application window has closed, but you can always plan ahead and apply for the next grant cycle.

The advantages of clinical research include making a significant contribution to the body of medical knowledge and obtaining an understanding of what it takes to conduct clinical research. Some students take a dedicated research year to gain experience in this area.

Review articles

A literature review is a collection and summarization of literature on an unresolved, controversial or novel topic. There are different categories of reviews, including meta-analyses, systematic reviews and traditional literature reviews, offering very high, high and modest evidentiary value, respectively. Advantages of review articles include the possibility of remote collaboration and developing expertise on the subject matter. Disadvantages can include the time needed to complete the review and the difficulty of publishing this type of research.

Forming an idea

Research can be inspiring and intellectually stimulating or somewhat painful and dull. It’s helpful to first find an area of medicine in which you are interested and willing to invest time and energy. Then, search for research opportunities in this area. Doing so will make the research process more exciting and will motivate you to perform your best work. It will also demonstrate your commitment to your field of interest.

Think carefully before saying yes to studies that are too far outside your interests. Having completed research on a topic about which you are passionate will make it easier to recount your experience with enthusiasm and understanding in interviews. One way to refine your idea is by reading a recent literature review on your topic, which typically identifies gaps in current knowledge that need further investigation.

Finding a mentor

As medical students, we cannot be the primary investigator on certain types of research studies. So, you will need a mentor such as a DO, MD or PhD. If a professor approaches you about a research study, say yes if it’s something you can commit to and find interesting.

More commonly, however, students will need to approach a professor about starting a project. Asking a professor if they have research you can join is helpful, but approaching them with a well-thought-out idea is far better. Select a mentor whose area of interest aligns with that of your project. If they seem to think your idea has potential, ask them to mentor you. If they do not like your idea, it might open up an intellectual exchange that will refine your thinking. If you proceed with your idea, show initiative by completing the tasks they give you quickly, demonstrating that you are committed to the project.

Writing and publishing

Writing and publishing are essential components of the scientific process. Citation managers such as Zotero, Mendeley, and Connected Papers are free resources for keeping track of literature. Write using current scientific writing standards. If you are targeting a particular journal, you can look up their guidelines for writing and referencing. Writing is a team effort.

When it comes time to publish your work, consult with your mentor about publication. They may or may not be aware of an appropriate journal. If they’re not, Jane , the journal/author name estimator, is a free resource to start narrowing down your journal search. Beware of predatory publishing practices and aim to submit to verifiable publications indexed on vetted databases such as PubMed.

One great option for the osteopathic profession is the AOA’s Journal of Osteopathic Medicine (JOM). Learn more about submitting to JOM here .

My experience

As a second-year osteopathic medical student interested in surgery, my goal is to apply to residency with a solid research foundation. I genuinely enjoy research, and I am a member of my institution’s physician-scientist co-curricular track. With the help of amazing mentors and co-authors, I have been able to publish a literature review and a case-series study in medical school. I currently have some additional projects in the pipeline as well.

My board exams are fast approaching, so I will soon have to adjust the time I am currently committing to research. Once boards are done, though, you can bet I will be back on the research grind! I am so happy to be on this journey with all my peers and colleagues in medicine. Research is a great way to advance our profession and improve patient care.

 Keys to success

Research is a team effort. Strive to be a team player who communicates often and goes above and beyond to make the project a success. Be a finisher. Avoid joining a project if you are not fully committed, and employ resiliency to overcome failure along the way. Treat research not as a passive process, but as an active use of your intellectual capability. Push yourself to problem-solve and discover. You never know how big of an impact you might make.

Disclaimers:

Human subject-based research always requires authorization and institutional review before beginning. Be sure to follow your institution’s rules before engaging in any type of research.

This column was written from the perspective from a current medical student with the review and input from my COM’s director of research and scholarly activity, Amanda Brooks, PhD. 

Related reading:

H ow to find a mentor in medical school

Tips on surviving—and thriving—during your first year of medical school

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By submitting my email address. i certify that i am 13 years of age or older, agree to recieve marketing email messages from the princeton review, and agree to terms of use., 6 ways for pre-meds to gain research experience.

Many med school applicants share  strong GPAs and impressive MCAT scores . So admissions officers look to other measures to make comparisons among candidates. Lab and research experience is one way to set yourself apart.

How Important is Research Experience to Med Schools?

Pre-med student gaining lab and resesarch experience

While research experience is not a requirement for admission to med school (unless you are a MD-PHD candidate), it can definitely be an advantage on your application. An interest in research shows off your curiosity, maturity, and work ethic—all qualities of students who are prepared to handle the challenges of med school.

If you are considering a career in academic medicine, you should try to get involved in research projects early in your undergraduate career. Bonus: Your research mentors are terrific people to ask for letters of recommendation !

Where to Find Research Opportunities

1. sit down with your professor..

Treat a professor to coffee and ask about research and special project opportunities for undergraduates in her lab or department. Touch base with any teaching and research assistants you work with through your pre-med courses , as well.

2. Check out various science department websites at your university.

Department websites usually list information on current research projects or can direct you to your school's offerings for funded or volunteer research. E-mail principal investigators (the lead researcher for a grant project administered by a university) at your school and ask how you can get involved with their study.

Read More: How To Make Your Med School Application Stand Out

3. Investigate summer programs.

Medical centers host summer research programs for undergraduates and even sometimes high school students. The National Science Foundation sponsors its Research Experience for Undergraduates program at many college campuses throughout the summer. Check out the AAMC database for summer undergraduate research programs geared toward students interested in scientific research.

4. Talk to your pre-med advisor or your college advisor.

These counselors are extremely knowledgeable about academic opportunities on campus and can point you in the right direction. You can also make an appointment to talk with a staff member at your college's career center.

5. Check out study abroad and internship programs.

Consider programs conducting research in the field. Internships at national laboratories and research facilities are also great options.  

6.  Consider taking a year off to participate in full-time research.

Applying to med school the summer before you senior year of college, essentially means you only have three years to pack in pre-req and extracurriculars. A gap year gives you time to devote to something you missed out—like conducting research— and strengthen your application.

What Types of Research Experiences Do Med Schools Look For?

Med schools typically find value in a wide range of experiences covering basic and social sciences, clinical, and humanities research. But a full year of research, preferably in lab setting, makes your research background stand out.

What if I don’t have Research Experience?

Med schools care about the sum of your experience. If you haven't had the opportunity or don't want to partake in research, dedicate your time to raising your MCAT scores or investing in your extracurriculars.  Our med school admission experts can help you position your accomplishments and experiences on your application.

That being said, research-oriented medical schools are also more likely to prioritize lab research experience during the admissions process. MD-PhD candidates will write an essay for their AMCAS application that highlights their research background.

Want to get an edge over the crowd?

Our admissions experts know what it takes it get into med school. Get the customized strategy and guidance you need to help achieve your goals.

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how to do medical research in high school

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Research for medical school admissions: what do you need to know.

how to do medical research in high school

Reviewed by:

Jonathan Preminger

Former Admissions Committee Member, Hofstra-Northwell School of Medicine

Reviewed: 4/25/24

There are several ways in which you can make your application for medical school more attractive to the eyes of admissions committees.

While research experience is not a requirement for most schools, having a research background that is sound, aligns with your major and interests, is fundamentally strong, and overall complements your application’s theme is a perfect way to be a competitive candidate and enhance your possibilities of getting into medical school.

This guide will teach you all that you need to know about research for medical school, ensuring you’ll gain successful and meaningful experiences.

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Importance of Research for Medical School‍

Infographic outlining the importance research for medical school and giving tips on how to land opportunities

Your MCAT , GPA, extracurriculars, and clinical experience all play a role in your admissions chances. But research is also key! Most but not all students accepted to medical school have research experience.

According to a survey of incoming medical students conducted by the AAMC , 60% of students participated in some kind of laboratory research for college students. Experts in the field have made their ideas about it very clear; Dr. Petrella, a Stanford University Ph.D. and mentor, states: 

“Our belief is that an exercise science curriculum provides students the opportunity to become responsible professionals of competence and integrity in the area of health and human performance.” 

Today, we’ll talk about how to prepare for and strategically use research to enhance your application and make it more interesting and rich in the eyes of the admissions committee. But first, take a quick look at why you should gain research experience in your undergraduate career. 

why research is important for medical school admissions

What Counts as Research for Medical School?‍

While most research is good research, some things should be taken into consideration before jumping into the next opportunity available: 

  • Clinical research is great but research in the humanities or social sciences also counts
  • Good research experience develops your writing skills, critical thinking skills, professionalism, integrity, and ability to analyze data
  • It’s important to contribute to the research for a long period of time—several months rather than a couple weeks
  • You can participate in research part-time or full-time; both count
  • You should get involved in research related to your major, desired career, and interests
  • Be committed and deeply involved in the research—you’ll be asked about it in interviews!
  • Being published as a top contributor of any related research papers looks the best 

Overall, there isn’t really “bad” research experience, so long as you’re committed, make clear contributions, and are genuinely passionate about the subject! 

How to Gain Research Experience as a Pre Med

There are several ways to become involved in research and find research opportunities during your undergraduate years. Research opportunities will be available through the university you’re attending, so make sure to maintain a good relationship and communication with your professors.

One of the best ways to secure a research position is to have a conversation with your professors. They may be looking for a student to help them with an upcoming project, and even if they don’t have any opportunities to offer you, they can easily refer to other staff members who might. 

Try navigating through your university’s website as well; many schools will have a student job board that may host research opportunities. For example, if you were a premed student at the University of Washington , you’d be able to check the Undergraduate Research Program (URP) database in order to filter and find research opportunities.

How Many Hours of Research Do You Need For Medical School? ‍

Since research is not a requirement at most medical schools, there’s no minimum number of hours you should be spending at the lab. Some students report entering medical school with over 2,000 hours of research experience, while others had no more than 400. 

This may seem like a lot but bear in mind that a semester or summer of research involvement sums up to around 500-800 hours. This can be more than enough to show your abilities, commitment, and critical thinking skills.

The hours you should dedicate to research widely depend on your personal circumstances and other aspects of your application. If you have the bandwidth to dedicate more hours to research, you should, but never compromise your grades for it. 

6 Types of Medical Research

There are six main types of research that pre-med students commonly participate in: 

Basic Science Research

Basic science research involves delving into the intricacies of biology in laboratory settings. It's one of the most common pre-med research opportunities and typically entails studying genes, cellular communication, or molecular processes.

Clinical Research

Clinical research is all about working with real patients to learn about health and illness. It's hands-on and great for getting a feel for healthcare. 

Public Health Research

Public health research focuses on analyzing population health trends and developing strategies for disease prevention and health promotion. It's a great area for pre-med students interested in community health, although it is a little harder to get involved in. 

Health Public Policy Research

Health public policy research examines the impact of healthcare regulations and policies on access to care and health outcomes. Although less common among pre-med students, it offers insights into the broader healthcare system, involving analyses of policy effectiveness and healthcare disparities.

Narrative Medicine Research

Narrative medicine research explores the role of storytelling and patient experiences in healthcare delivery. It's a more human side of medicine, focusing on empathy and connection. 

Artificial Intelligence Research

Artificial intelligence research can be difficult for pre-meds to get involved in, but it offers innovative solutions to complex medical problems, such as developing AI algorithms for disease diagnosis and treatment planning.

Tips to Make the Best out of Research Hours 

Now that we've covered the importance of research experience for med school application, we'll go over some tips to help you make the most of your research experience!

Have Noteworthy Research Experience

Having noteworthy research experience is a plus in your application, but it doesn’t end here. The ultimate goal of research is to actually become involved in the most recent projects, discoveries, and questions in your field of study, and prepare you for potential research later in your graduate career.

Use Research as an Opportunity to Gain Skills

Make your best effort to see research experience not only as a way to make your resume and application look better, but also as an opportunity to gain skills and face challenges that will help you become a dedicated professional, and will help you succeed in any your future endeavors. 

Be Clear With Your Goals

Before getting started with your research hours, make sure the research question is perfectly clear to you, and that you’re familiar and interested in what the research is aiming to find or prove. By doing this, you’ll be off to a great start, and your research experience will be valuable from the beginning.

Understand the Project and Be Engaged

Once you’re involved in research, make sure you try your best to perfectly understand every part of it. Shallow and meaningless research experiences won’t get you very far.

During your interview you'll be asked about the research project – regardless of your level of contribution, it’s important for you to be clear, confident, and perfectly articulate to make yourself a competitive candidate.

Take Your Experience Seriously

Also, take your time at the lab very seriously. Try approaching your research contribution as a job; show up in time just like you would show up in time for work, put your best effort in it, and above all, be professional. 

Build Relationships With Your Supervisors

Another tip for maximizing your research experience is to make a connection and form a relationship with the mentor or the professor that will, or is already working with you. By forming strong bonds and relationships, you’ll have the opportunity to ask your mentor for a letter of recommendation.

So, do take every hour spent seriously and work hard to make a good impression. This way, you’ll kill two birds with one stone: you’ll gain research experience while obtaining strong recommendations.

What Kind of Research do Medical Schools Prefer? (Science vs Non-Science)‍

That is a somewhat tricky question. The simple answer is that any research that can show your involvement and commitment and aligns with the theme of your application is beneficial. However, there are a lot of layers to it. 

Probably the most common type of research among applicants –which is also highly valued by medical schools – is science and lab research. If you’re a science major in college, this is probably the way you’d want to go; laboratory-based research. 

With that said, if your major is in the social sciences or humanities, getting involved in research related to your major and your interests is something that medical schools will find attractive.

After all, the majority of schools use a holistic approach to admissions and want their potential candidates to be widely and well-educated individuals.

1. Is Research Experience More Important Than Clinical Experience For Medical School?‍

The short answer to this is no. Even though the majority of applicants have research experience, for many deans of admissions, clinical experience is equally and sometimes even more valuable. The clinical experience involves patient interaction, which is undoubtedly crucial preparation for a life-long career as a physician.

However, getting your first research experience as early as possible in your undergraduate years will help you determine if research is something you’d like to pursue in the future. Plus, it will make it easier for you to secure more research positions in your graduate years, so you should definitely go for it if it's of your interest. 

2. Is Research Experience More Important Than Physician Shadowing?

While both experiences are relevant, research has the added benefit of allowing you to gain hands-on experience. However, don’t forget that doctor shadowing also adds a lot of value to your application, since it serves the purpose of actually seeing what being a physician is, and such experience could determine your interest in moving forward. 

You should also take into account what your medical school of choice expects. For example, for research-focused schools like the Mayo Clinic , research experience will definitely be more important and you should plan on putting most of your energy there. ‍

3. Should I Take A Gap Year Before Medical School To Gain Research Hours?‍

Taking a gap year gives you the opportunity to refine your application and fully focus on what you want to improve. Whether it’s worth it or not depends on your personal and academic circumstances. Remember, it’s not necessarily about how many hours you complete, but the level of contribution you make and your interest in it!

4. Should I Participate In Many, Short-Lived Research Experiences Or In A Few Long Ones?‍

Always choose quality over quantity when it comes to research experience. One long research experience will impress the admissions committee far more than several short ones! More time spent on a project often means greater contributions made, and it demonstrates interest, persistence, and resilience.

5. Should I Look For Research Opportunities Even If My GPA Is A Bit Low?‍

If you’ve gone through a hard time and your GPA is suffering a little bit, definitely focus your energy on that before committing to long hours in the lab. Your GPA and MCAT scores are the non-arguable parts of your application; make sure these are as impeccable as possible, and as soon as there’s an improvement, move on to research.

That doesn’t mean that you should completely forget about the “extras” of your application; as long as you keep a balance between a good GPA, scores, work, and extracurriculars, you’ll be on the right path to creating a competitive application. ‍

6. What Does It Mean To Be Published In Research? Is It Important To Medical Schools?‍

Being published means that your name appears on written documents about research, and it is, indeed, important, but not necessary. We’re not talking about being the first author in a publication, since this is almost impossible for an undergraduate student. 

However, appearing as a co-author on any presentation, publication, or poster will help you build a reputation.

7. What Should I Do If I Don’t Have Research Experience?‍

Ultimately, if you don’t have any research experience and do not have time or do not plan on being part of any research, focus and invest time in your clinical experience as well as volunteering and community service. Also, work on maintaining a good GPA and improving your MCAT score.

Keep in mind, though, that MD-PhD candidates do need to get involved in research before applying, and a big emphasis should be placed on research in these cases. 

8. Does Clinical Research Count Also As Clinical Experience?

Clinical research can count as both clinical experience and research experience in your AMCAS application.

9. Is Research Required For Medical School?

Research experience is not required for most medical schools. However, having research experience will help you stand out and present yourself as a more competitive candidate during the application process.

Final Thoughts‍

Participating in research for medical school can play an important role in the quality of your application. For this reason, knowing how to make your experiences as valuable and rich as possible will play a key role in ensuring the research complements your application and overall profile. 

Research is the perfect way to build a strong skill set that will aid you as a medical student and make you a better physician! 

how to do medical research in high school

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willpeachMD

Research Heavy Med Schools (8 Important Facts)

For many aspiring physicians, doing some form of academic or scientific research is one way of making a med school application competitive. But what about so-called “research-heavy” med schools? How do they work?

What is a “research-heavy” med school?

A research-heavy med school is one that is considered to strongly favor pre-med applicants with impressive research credentials or hours. Students with publications, or those making strong contributions to such projects, are said to be good fits for these types of schools.

But just because you don’t fit the criteria, does that mean you shouldn’t bother applying?

That’s what this article hopes to find out!

Here’s what else we’ll cover:

How to identify a research-heavy med school

  • Who should best target them (and who shouldn’t)
  • Why they care about research

As a med student myself, and one who’s interested in doing research throughout my future medical career, I can appreciate how useful some of the answers to these questions might be.

Ready to jump in? Let’s go.

Although it’s impossible to know the degree to which a certain med school is research-heavy, it is possible to get a rough idea.

The first place to look is at the most recent list of National Insitute of Health (NIH) funded institutions. This details several medical schools that take funding for extramural research in the form of grants.

2020’s list ( Source ) features the following institutions in the top 50.

Here they are in descending order (medical schools are bolded):

50Dana-Farber Cancer Institute$168,968,587 through 265 awards
49The Scripps Research Institute$170,903,082 through 241 awards
48 $175,249,359 through 399 awards
47Sloan-Kettering Institute$176,889,703 through 291 awards
46 $177,488,241 through 346 awards
45 $181,853,504 through 93 awards
44 $182,500,010 through 443 awards
43 $185,644,333 through 335 awards
42Boston Children’s Hospital$192,682,552 through 366 awards
41FHI 360 (formerly Family Health International)$192,932,746 through 6 awards
40 $200,332,911 through 409 awards
39 $204,180,928 through 509 awards
38 $206,405,214 through 471 awards
37Indiana University-Purdue University at Indianapolis (IUPUI)$214,313,650 through 406 awards
36 $214,958,510 through 491 awards
35 $217,849,516 through 446 awards
34 $220,691,792 through 426 awards
33 $237,849,512 through 484 awards
32Mayo Clinic (Rochester, MN)$261,314,178 through 379 awards
31 $267,091,236 through 692 awards
30 $275,202,636 through 318 awards
29 $282,423,540 through 473 awards
28 $282,673,537 through 513 awards
27 $291,827,756 through 582 awards
26 $301,689,095 through 515 awards
25 $303,925,843 through 516 awards
24 $305,019,304 through 608 awards
23Brigham and Women’s Hospital$308,419,887 through 579 awards
22 $316,902,468 through 686 awards
21 $333,297,150 through 605 awards
20 $350,777,315 through 640 awards
19RTI International (Research Triangle Institute)$355,059,620 through 84 awards
18 $357,135,751 through 507 awards
17 $429,776,965 through 764 awards
16 $456,919,580 through 919 awards
15 $476,884,458 through 1,011 awards
14 $478,435,137 through 978 awards
13 $481,845,918 through 923 awards
12 $484,735,147 through 847 awards
11 $496,363,341 through 995 awards
10 $512,611,430 through 1,010 awards
9 $505,071,973 through 952 awards
8 $507,399,383 through 1,076 awards
7Massachusetts General Hospital$511,815,008 through 944 awards
6 $553,442,380 through 1,175 awards
5 $579,203,245 through 1,238 awards
4Fred Hutchinson Cancer Research Center$598,904,570 through 274 awards
3 $629,215,516 through 835 awards
2 $636,062,320 through 1,306 awards
1 $722,890,586 through 1,339 awards

Although this list isn’t conclusive, it can be used to get an idea of which schools depend heavily on research funding.

Note that U.S. News data from the same year, although it has certain discrepancies, rank most of these schools similarly.

The big difference being ranking Harvard University at the top, followed by the University of Washington and then UCLA ( Source ).

How accurate is this data?

There are a couple of problems with using NIH’s data to estimate just how research-heavy a school might be.

The first problem revolves around affiliations.

Harvard University, for example, has over 15 affiliated hospitals and research institutes. When research money is spread out across each, the actual amount Harvard Medical School receives is significantly lower.

The second is the assumption that funding equates to selection bias.

Just because a certain school on this list appears to get a lot of research funding, doesn’t mean it’ll necessarily admit applicants based on research experience.

The admissions criteria for most of these schools are typically much more complicated than that.

Do all these schools favor research-heavy applications?

The only way to know for sure is to speak to past and present alumni who may be better positioned to give an opinion.

Asking them about their level of research experience prior to getting accepted into medicine, and seeing if you can spot a potential trend, is probably the best way to do this.

Here’s the kind of questions you may want to ask:

  • How many research hours did you log before being accepted?
  • What fields (and what insitutions) did you complete research at?
  • Did you get any publications (and, if so, where)?
  • What’s your gut feeling in terms of how much emphasis the admissions team puts on research?

Because medical schools won’t usually state how much weighting they give to candidates with a strong research background in their admissions criteria (instead commonly referring to it as a “preference”), it’s hard to give a direct answer.

Most of what we know is typically assumed.

Who should tailor an application toward a research-heavy med school?

Clearly, if you have great research experience (and you feel it could be a strong differentiator), you should not be deterred from applying to any of the supposed research-heavy schools on the lists above.

Being able to detail it on your personal statement or extracurriculars section can certainly help give you a competitive edge.

But there is a right way to go about it.

You don’t want to exaggerate your involvement or show a lack of understanding. Any scheduled interviews will quickly expose either.

For more tips on how best to write (and talk) about your research experiences, take a look at the following article…

Related : How To Write About Research For Medical School

Should you apply to them if you don’t have publications?

You should definitely still apply to a research-heavy medical school even if you don’t have publications.

Because not all publications are equal, coupled with the fact that a publication doesn’t necessarily suggest your level of contribution, understanding, and involvement, you can’t place too much importance on them.

Admissions teams understand this and will look at your application as a whole to see if there other areas (and other extracurriculars) where you stand out. I talk more about this here; No Research Experience For Medical School? (7 Things To Do) .

And while of course being a 1st author, 6th author or even an abstract can look seriously impressive (even more so if it’s in a particularly esteemed journal), it is pretty rare as far as pre-meds go.

So don’t see your lack of publications as too much of an impediment!

What is the “average” research experience for these schools?

Average research experience is something of a difficult question.

Because many factors go into determining the quality of research, it’s also something of a redundant point.

Here are some common variables:

  • The amount of hours of research
  • Number of labs
  • Depth of the work
  • Objective importance of the work
  • Field of research

Because no one research project looks the same (based on these points), it’s incredibly difficult to give any tangible average.

I talk more about this in the article below…

Related : How Many Hours Of Research For Medical School Is Best?

Why is research such a big thing?

Although having done research is not required to apply for med school, it’s still a big deal when it comes to any discussion surrounding the topic.

The reason why many colleges care is that research funding helps boost several factors that help elevate their status in terms of international rankings.

More funding leads to more opportunities like…

  • Improving facilities and resources
  • Attracting the best teachers and professors
  • Increased commercial opportunities

And then of course there is med school ranking themselves.

These go a long way to attracting top-caliber applicants!

If you enjoyed this article, you might find the following useful:

  • What Counts As Research Experience For Medical School? (Explained)
  • MD/Ph.D. Programs: Everything You Need To Know

Will

Born and raised in the UK, Will went into medicine late (31) after a career in journalism. He’s into football (soccer), learned Spanish after 5 years in Spain, and has had his work published all over the web. Read more .

High School Students Gain Introduction to Kinesiology Concepts through Summer Pre-College Programs

Photo of students conducting exercises during Pre-College at UMass Amherst summer program

This July, kinesiology faculty and graduate students introduced high school students from around the world to core kinesiology concepts through a series of summer pre-college residential programs. Students enrolled in intensive, two-week courses on subjects that included Kinesiology: Pathway to the Medical Professions , Psychology of the Human-Animal Bond , and Sports Performance .

42 students from across the U.S. and six different countries enrolled in Kinesiology: Pathway to the Medical Professions , instructed by senior lecturer II Judi LaBranche . The two week-long course showed students how kinesiology can lead to a medical career, including research in physiology, metabolism, biomechanics, nursing, physical therapy, occupational therapy, physician assistant, physical activity, and neuroscience.

“Back home in the Virgin Islands I play on a national soccer team,” said Charlotte Nairns, a student from the Virgin Islands. “Our doctor has a degree in kinesiology and has been teaching me a lot about it. It’s interesting to me, so I want to study it more. This program has allowed me to do that. I especially like how it’s hands on. We learn about a topic in the classroom and then we get to physically do what we just learned and apply it in real time.”

Group of students measuring their heart rate during an exercise for UMass's Pre-College program

Hosted in the Totman Building by LaBranche and graduate student assistants, the program provided students with hands-on experience in dissections, health assessments, and current health guidelines. 

“I’m a swimmer and a lot of these exercises will help me in my own training,” explained Noah Chetlen, who traveled from Hershey, Pennsylvania for the program. “We learned how to develop fitness plans and the science behind muscle fatigue and how to battle that. I’m looking forward to using that knowledge to make me a better swimmer.”

Photo of students practicing the proper form to lift weights

The Psychology of the Human-Animal Bond, instructed by doctoral candidate Ann-Marie Sylvia, focused on the human-animal connection and its benefit to mental and physical health with an emphasis on neurodivergent populations (e.g., autism, ADHD, anxiety, dementia). Hosted at Chestnut Woods Farm in Granby, MA, the course enrolled 16 high school students who were given the opportunity to perform field research and were trained to assist as side walkers or equine leaders for the youth involved.

Group photo of students at Chestnut Woods Farm in Granby

“My research interest focuses on the intersection of physical activity and neurodivergence,” noted Sylvia. “We decided to run this program because it was the perfect opportunity to introduce interested high school students to the psychology of the human-animal bond and recognize the power of physical activity, not only for overall health outcomes, but also for the trait and characteristics of neurodivergence.” 

Senior lecturer II and undergraduate program director Thomas St. Laurent led the course on Sports Performance . The program provided a hands-on opportunity for 12 high school students to enhance their own athletic performance and explore a career in sports performance. Students learned about different training techniques, engaged in skill workshops, and learned the science behind performance strategies. It also offered students a unique opportunity to utilize UMass Amherst’s on-campus training facilities for the practical sessions. 

Students left excited to apply the advanced strategies they learned to their sports. One student shared, “I loved how we got to train like college athletes and understand what it takes to compete at a higher level. The workshops were eye-opening, and I feel more prepared than ever to pursue my goals!”

“The program aimed to teach them how to enhance their athletic abilities and give them a taste of college life and the supportive community they can expect from UMass,” said St. Laurent. “We’re excited to see these young athletes take their newfound skills and confidence back to their high school teams. We hope this experience will inspire them to consider UMass for their future college education. The department is excited to offer the program again next summer and is creating a Sports Performance training area to enhance the hands-on workshops we can offer.”

Photo of Thomas St. Laurent

The Summer Pre-College Residential Programs are open to rising 10th through 12th graders. They allow students to experience college life and explore their interests in over 25 topics including STEM, design, business, and public health. Many students use the programs to explore UMass and the School of Public Health and Health Sciences, and to build experience for their college applications. 

“After graduating from high school, I want to apply to nursing school,” said Ahsyra Robinson Noel of Boston, MA. “My school counselor told me about the Pre-College Program and helped me get in. This will be great to tell nursing schools about the experiences I had. This is a great opportunity outside of school to get a better understanding of what the medical field will be like.”

LaBranche was impressed with the overall level of student learning and instructional outcomes over the two weeks she instructed. “They did great,” she said. “We look forward to seeing some of these students as UMass students soon.” 

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Study reveals the benefits and downside of fasting

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Low-calorie diets and intermittent fasting have been shown to have numerous health benefits: They can delay the onset of some age-related diseases and lengthen lifespan, not only in humans but many other organisms.

Many complex mechanisms underlie this phenomenon. Previous work from MIT has shown that one way fasting exerts its beneficial effects is by boosting the regenerative abilities of intestinal stem cells, which helps the intestine recover from injuries or inflammation.

In a study of mice, MIT researchers have now identified the pathway that enables this enhanced regeneration, which is activated once the mice begin “refeeding” after the fast. They also found a downside to this regeneration: When cancerous mutations occurred during the regenerative period, the mice were more likely to develop early-stage intestinal tumors.

“Having more stem cell activity is good for regeneration, but too much of a good thing over time can have less favorable consequences,” says Omer Yilmaz, an MIT associate professor of biology, a member of MIT’s Koch Institute for Integrative Cancer Research, and the senior author of the new study.

Yilmaz adds that further studies are needed before forming any conclusion as to whether fasting has a similar effect in humans.

“We still have a lot to learn, but it is interesting that being in either the state of fasting or refeeding when exposure to mutagen occurs can have a profound impact on the likelihood of developing a cancer in these well-defined mouse models,” he says.

MIT postdocs Shinya Imada and Saleh Khawaled are the lead authors of the paper, which appears today in Nature .

Driving regeneration

For several years, Yilmaz’s lab has been investigating how fasting and low-calorie diets affect intestinal health. In a 2018 study , his team reported that during a fast, intestinal stem cells begin to use lipids as an energy source, instead of carbohydrates. They also showed that fasting led to a significant boost in stem cells’ regenerative ability.

However, unanswered questions remained: How does fasting trigger this boost in regenerative ability, and when does the regeneration begin?

“Since that paper, we’ve really been focused on understanding what is it about fasting that drives regeneration,” Yilmaz says. “Is it fasting itself that’s driving regeneration, or eating after the fast?”

In their new study, the researchers found that stem cell regeneration is suppressed during fasting but then surges during the refeeding period. The researchers followed three groups of mice — one that fasted for 24 hours, another one that fasted for 24 hours and then was allowed to eat whatever they wanted during a 24-hour refeeding period, and a control group that ate whatever they wanted throughout the experiment.

The researchers analyzed intestinal stem cells’ ability to proliferate at different time points and found that the stem cells showed the highest levels of proliferation at the end of the 24-hour refeeding period. These cells were also more proliferative than intestinal stem cells from mice that had not fasted at all.

“We think that fasting and refeeding represent two distinct states,” Imada says. “In the fasted state, the ability of cells to use lipids and fatty acids as an energy source enables them to survive when nutrients are low. And then it’s the postfast refeeding state that really drives the regeneration. When nutrients become available, these stem cells and progenitor cells activate programs that enable them to build cellular mass and repopulate the intestinal lining.”

Further studies revealed that these cells activate a cellular signaling pathway known as mTOR, which is involved in cell growth and metabolism. One of mTOR’s roles is to regulate the translation of messenger RNA into protein, so when it’s activated, cells produce more protein. This protein synthesis is essential for stem cells to proliferate.

The researchers showed that mTOR activation in these stem cells also led to production of large quantities of polyamines — small molecules that help cells to grow and divide.

“In the refed state, you’ve got more proliferation, and you need to build cellular mass. That requires more protein, to build new cells, and those stem cells go on to build more differentiated cells or specialized intestinal cell types that line the intestine,” Khawaled says.

Too much of a good thing

The researchers also found that when stem cells are in this highly regenerative state, they are more prone to become cancerous. Intestinal stem cells are among the most actively dividing cells in the body, as they help the lining of the intestine completely turn over every five to 10 days. Because they divide so frequently, these stem cells are the most common source of precancerous cells in the intestine.

In this study, the researchers discovered that if they turned on a cancer-causing gene in the mice during the refeeding stage, they were much more likely to develop precancerous polyps than if the gene was turned on during the fasting state. Cancer-linked mutations that occurred during the refeeding state were also much more likely to produce polyps than mutations that occurred in mice that did not undergo the cycle of fasting and refeeding.

“I want to emphasize that this was all done in mice, using very well-defined cancer mutations. In humans it’s going to be a much more complex state,” Yilmaz says. “But it does lead us to the following notion: Fasting is very healthy, but if you’re unlucky and you’re refeeding after a fasting, and you get exposed to a mutagen, like a charred steak or something, you might actually be increasing your chances of developing a lesion that can go on to give rise to cancer.”

Yilmaz also noted that the regenerative benefits of fasting could be significant for people who undergo radiation treatment, which can damage the intestinal lining, or other types of intestinal injury. His lab is now studying whether polyamine supplements could help to stimulate this kind of regeneration, without the need to fast.

“This fascinating study provides insights into the complex interplay between food consumption, stem cell biology, and cancer risk,” says Ophir Klein, a professor of medicine at the University of California at San Francisco and Cedars-Sinai Medical Center, who was not involved in the study. “Their work lays a foundation for testing polyamines as compounds that may augment intestinal repair after injuries, and it suggests that careful consideration is needed when planning diet-based strategies for regeneration to avoid increasing cancer risk.”

The research was funded, in part, by Pew-Stewart Scholars Program for Cancer Research award, the MIT Stem Cell Initiative, the Koch Institute Frontier Research Program via the Kathy and Curt Marble Cancer Research Fund, and the Bridge Project, a partnership between the Koch Institute for Integrative Cancer Research at MIT and the Dana-Farber/Harvard Cancer Center.

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A new study led by researchers at MIT suggests that fasting and then refeeding stimulates cell regeneration in the intestines, reports Katharine Lang for Medical News Today . However, notes Lang, researchers also found that fasting “carries the risk of stimulating the formation of intestinal tumors.” 

Prof. Ömer Yilmaz and his colleagues have discovered the potential health benefits and consequences of fasting, reports Max Kozlov for Nature . “There is so much emphasis on fasting and how long to be fasting that we’ve kind of overlooked this whole other side of the equation: what is going on in the refed state,” says Yilmaz.

MIT researchers have discovered how fasting impacts the regenerative abilities of intestinal stem cells, reports Ed Cara for Gizmodo . “The major finding of our current study is that refeeding after fasting is a distinct state from fasting itself,” explain Prof. Ömer Yilmaz and postdocs Shinya Imada and Saleh Khawaled. “Post-fasting refeeding augments the ability of intestinal stem cells to, for example, repair the intestine after injury.” 

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