biotechnological research papers

Biotechnology and Bioprocess Engineering

  • Gyoo Yeol Jung

Societies and partnerships

New Content Item

Latest issue

Volume 29, Issue 2

Latest articles

Homotaurine exhibits contrasting effects of drd1-mediated thermogenesis-related regulators in c2c12 myoblasts and 3t3−l1 white adipocytes.

  • Kiros Haddish
  • Jong Won Yun

biotechnological research papers

Establishment of a new promoter trapping vector using 2A peptide

  • Eun Seon Song
  • Yun Haeng Lee
  • Joon Tae Park

biotechnological research papers

Cell line-specific impact of dexamethasone on the bioprocessing of Chinese hamster ovary cells

  • Yeong Bin An
  • Da Eun Kang
  • Jong Kwang Hong

biotechnological research papers

Study on the S239D/I332E mutation effect on the kinetics of Fc–Fc receptor binding through transition complex theory

  • Petrina Jebamani

biotechnological research papers

Inhibitory effects of bromoindoles on Escherichia coli O157:H7 biofilms

  • Hyejin Jeon
  • Bharath Reddy Boya

biotechnological research papers

Journal updates

About the society.

Korean Society for Biotechnology and Bioengineering

New Content Item

The Society aims to contribute to the advancement and distribution of biotechnology, and further academic cooperation and friendship among the members...

Top 10 Most-Cited Articles in Biotechnology and Bioprocess Engineering

The lists of top 10 most cited articles published in Biotechnology and Bioprocess Engineering.

Journal information

  • Biological Abstracts
  • Chemical Abstracts Service (CAS)
  • EI Compendex
  • Google Scholar
  • IFIS Publishing
  • Japanese Science and Technology Agency (JST)
  • Korea Citation Index (KCI)
  • OCLC WorldCat Discovery Service
  • Science Citation Index Expanded (SCIE)
  • Semantic Scholar
  • TD Net Discovery Service
  • UGC-CARE List (India)

Rights and permissions

Springer policies

© The Korean Society for Biotechnology and Bioengineering

  • Find a journal
  • Publish with us
  • Track your research

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • View all journals
  • Explore content
  • About the journal
  • Publish with us
  • Sign up for alerts
  • Perspective
  • Published: 09 November 2017

Ethical principles for the use of human cellular biotechnologies

  • Paul Root Wolpe 1 ,
  • Karen S Rommelfanger 1 &

the Drafting and Reviewing Delegates of the BEINGS Working Groups

Nature Biotechnology volume  35 ,  pages 1050–1058 ( 2017 ) Cite this article

6360 Accesses

13 Citations

41 Altmetric

Metrics details

  • Biotechnology
  • Cell biology

Recent developments in bioengineering promise the possibility of new diagnostic and treatment strategies, novel industrial processes, and innovative approaches to thorny problems in fields such as nutrition, agriculture, and biomanufacturing. As modern genetics has matured and developed technologies of increasing power, debates over risk assessments and proper applications of the technology, and over who should have decision-making power over such issues, have become more prominent. Recently, some scientists have advocated that ethicists “step out of the way,” whereas others have called for greater ethical scrutiny, or even for moratoria on some lines of research 1 , 2 . As a community, however, we must together determine the proper application of these powerful biological tools. This paper, a consensus statement of a group of interdisciplinary delegates drawn from the top biotech-producing countries of the world, offers a set of ethical principles to contribute to the ethical conversation about human cellular biotechnological research moving forward.

This is a preview of subscription content, access via your institution

Access options

Access Nature and 54 other Nature Portfolio journals

Get Nature+, our best-value online-access subscription

24,99 € / 30 days

cancel any time

Subscribe to this journal

Receive 12 print issues and online access

195,33 € per year

only 16,28 € per issue

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF

Prices may be subject to local taxes which are calculated during checkout

US Department of Energy, Office of Science. Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options (US Department of Energy, Office of Science, 2014).

Daley, G.Q. et al. Setting global standards for stem cell research and clinical translation: the 2016 ISSCR Guidelines. Stem Cell Rep. 6 , 787–797.

Article   Google Scholar  

Committee on Science, Technology, and Law; Policy and Global Affairs; National Academies of Sciences, Engineering, and Medicine. International Summit on Human Gene Editing: A Global Discussion (National Academies Press, Washington, DC, USA, 2015).

Baltimore, D. et al. A prudent path forward for genomic engineering and germline gene modification. Science 348 , 36–37 (2015).

Article   CAS   Google Scholar  

Chan, S. et al. Genome editing technologies and human germline genetic modification: the hinxton group consensus statement. Am. J. Bioeth. 15 , 42–47 (2015).

Caplan, A. & Plunkett, C. Get out of the way of human genetic engineering? Unwise and uncalled for. Pharma Healthcare (2016).

Google Scholar  

Miller, H.I. We desperately need bioethicists... to get out of the way of gene therapy. Forbes (1 June 2016).

Anonymous. Japan panel greenlights gene editing of human eggs for basic study. The Japan Times (22 April 2016).

Collins, F.S. Statement on NIH funding of research using gene-editing technologies in human embryo (The NIH Director, US National Institutes of Health, 28 April 2015).

Hyun, I., Wilkerson, A. & Johnston, J. Embryology policy: revisit the 14-day rule. Nature 533 , 169–171 (2016).

Charo, R.A. & Greely, H.T. CRISPR critters and CRISPR cracks. Am. J. Bioeth. 15 , 11–17 (2015).

Becker, R. US government approves transgenic chicken. Nature (9 December 2015).

Kuzma, J. Policy: reboot the debate on genetic engineering. Nature 531 , 165–167 (2016).

Akbari, O.S. et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science 349 , 927–929 (2015).

Pinker, S. The Better Angels of Our Nature: Why Violence Has Declined (Penguin, 2011).

Gauchat, G. Politicization of science in the public sphere a study of public trust in the United States, 1974 to 2010. Am. Sociol. Rev. 77 , 167–187 (2012).

Garland-Thomson, R. The case for conserving disability. J. Bioeth. Inq. 9 , 339–355 (2012).

Haraway, D. Situated knowledges: the science question in feminism and the privilege of partial perspective. Fem. Stud. 14 , 575–599 (1988).

Kuhn, T.S. The Structure of Scientific Revolutions (University of Chicago Press, Chicago, USA, 1962).

Wolpe, P.R. Reasons scientists avoid thinking about ethics. Cell 125 , 1023–1025 (2006).

UNESCO International Bioethics Committee. Report of the IBC on Updating Its Reflection on the Human Genome and Human Rights (UNESCO, 2015).

Hamzelou, J. Let people most affected by gene editing write CRISPR rules. New Sci. (29 April 2016).

Council of Europe. Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine (Council of Europe, Oviedo, Spain, 1997).

van Bubnoff, A. The 1918 flu virus is resurrected. Nature 437 , 794–795 (2005).

Grady, C. et al. Broad consent for research with biological samples: workshop conclusions. Am. J. Bioeth. 15 , 34–42 (2015).

Drabiak-Syed, K. Lessons from Havasupai Tribe v. Arizona State University Board of Regents: recognizing group, cultural, and dignity harms as legitimate risks warranting integration into research practice. J. Health Biomed. L. 6 , 175–225 (2010).

Kowal, E. Orphan DNA: indigenous samples, ethical biovalue and postcolonial science. Soc. Stud. Sci. 43 , 577–597 (2013).

United Nations General Assembly. Declaration on the rights of Indigenous peoples, Resolution 61.295, 13 (2007).

Truog, R.D., Kesselheim, A.S. & Joffe, S. Research ethics. Paying patients for their tissue: the legacy of Henrietta Lacks. Science 337 , 37–38 (2012).

Ray, S., Moiyadi, A. & Srivastava, S. Epidemiology: Biorepositories for cancer research in developing countries. Nat. Rev. Clin. Oncol. 10 , 434–436 (2013).

Saini, K.S., Saini, M.L. & Marbaix, E. Biobanking in the era of precision oncology. Indian J. Med. Paediatr. Oncol. 36 , 1–2 (2015).

Sgaier, S.K. et al. Public health. Biobanks in developing countries: needs and feasibility. Science 318 , 1074–1075 (2007).

Singer, P.A. & Daar, A.S. Harnessing genomics and biotechnology to improve global health equity. Science 294 , 87–89 (2001).

Fischhoff, B. The realities of risk-cost-benefit analysis. Science 350 , aaa6516 (2015).

Download references

Acknowledgements

BEINGS was made possible by grants from the Coca-Cola Foundation, Emory University, The Marcus Foundation, Georgia Research Alliance, Wipro Limited, King & Spalding Law Firm, the Metro Atlanta Chamber of Commerce, Southwest Airlines, Sanofi, Air France, The Embassy of the Republic of France, the Atlanta Clinical and Translational Science Institute, Central Atlanta Progress, and Biofaction. Academic partners included the Georgia Institute of Technology, the University of Georgia, Kennesaw State University, Brenau University, Mercer University, Agnes Scott College, Columbia Theological Seminary, Georgia College, Georgia Gwinnett College, Georgia State University, Morehouse School of Medicine, University of Northern Georgia, Oglethorpe University Savannah College of Art and Design, and the University of West Georgia.

Author information

Authors and affiliations.

Paul Root Wolpe and Karen S. Rommelfanger are at the Center for Ethics, Emory University, Atlanta, Georgia, USA.,

Paul Root Wolpe & Karen S Rommelfanger

You can also search for this author in PubMed   Google Scholar

Corresponding author

Correspondence to Paul Root Wolpe .

Ethics declarations

Competing interests.

One author, Karol Estrada, reports receiving salary and stocks from Biogen.

Rights and permissions

Reprints and permissions

About this article

Cite this article.

Wolpe, P., Rommelfanger, K. & the Drafting and Reviewing Delegates of the BEINGS Working Groups. Ethical principles for the use of human cellular biotechnologies. Nat Biotechnol 35 , 1050–1058 (2017). https://doi.org/10.1038/nbt.4007

Download citation

Published : 09 November 2017

Issue Date : November 2017

DOI : https://doi.org/10.1038/nbt.4007

Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

This article is cited by

Nano-enabled cellular engineering for bioelectric studies.

  • Clementene Clayton

Nano Research (2020)

Quick links

  • Explore articles by subject
  • Guide to authors
  • Editorial policies

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

biotechnological research papers

journal description

Biotechnological Research (ISSN 2395-6763) is an open access international peer reviewed journal. The Journal publishes quarterly (4 times an year) innovative research findings from applied biology fields. Main areas journal focuses: (1) Classical Biotechnology which includes the production of animal, plant and microbial bio-products, production optimization and their applications; (2) Environmental Biotechnology which includes bio remediation, waste management, pollutants, hazards and their remedies; (3) Medical Biotechnology dealing with diseases and their solutions using biotechnological tools, current developments in medical diagnostics like innovative ideas, techniques, instruments and so on; (4) Bioinformatics which use of bioinformatics tools in drug designing, prediction of protein structures, development of new algorithms for innovative tools, databases etc.; (4) Plant Biotechnology: latest developments from plant biology including plant tissue culture, stress resistance, hybridization, improvement of crop variety, genetic variation studies and so on; (5) New Biology including advanced molecular biology, genetic engineering and latest technologies which could be revolutionary in the future.

latest issues

Biotechnological research, featured articles, genetic variations in the orf7a protein of sars-cov-2 and its possible role in vaccine development.

The recurrent mutations in Orf7a of SARS-CoV-2 provide a deep understanding of its role in the virus�host interactions. Findings of our study revealed that the predicted epitopes could be promising candidates for a vaccine against COVID-19 infections.....

Pharmacological intervention of various Indian medicinal plants in combating COVID-19 infection

Special emphasis has been given on the antiviral activities of these plants against SARS-CoV-2, highlighting their efficacy as potential drug candidates.

Transplantation of mesenchymal stem cell sheet to treat acute hind-limb ischemia: A preclinical study

Fi-MSC sheet transplantation positively reduced injury and improved blood perfusion ALI in the Swiss mouse model...

Morphokinetic parameters comparison between euploid and aneuploid blastocysts

In this study, we found no difference in the morphokinetic parameters between euploid and aneuploid embryos....

Docking studies, synthesis, characterization, and cytotoxicity activity of new bis-chalcones derivatives

The cytotoxic activity of all the synthesized compounds was evaluated against MCF-7 breast cancer cell lines. Compounds 5 and 6 were found to have IC50 values of about 20 �M. These compounds are good candidates to be selected for further studies to develop anticancer drugs...

latest articles

Anti-giardia activity of a methanol extract of anvillea radiata.

Summary: This study aimed to evaluate the antiparasitic activity of Anvillea radiata plant extracts from the traditional pharmacopoeia by searching for new antiparasitic molecules. It seemed important to us to explore the nature of the natural antiparasitic substances in some Asteraceae of traditional Saharan medicine.

Efficacy of Activated Autologous Platelet-Rich Plasma in The Treatment of Diabetic Foot Ulcers: An Evidence-Based Brief Literature Review

Summary: Diabetic foot ulcers (DFUs) present as a debilitating complication of diabetes which approximately affects 6.3% of the global population with significant mortality and morbidity consequences. While one-third of the total cost of diabetic care goes to DFU treatment, 20% patients have unresolved ulcers, while 40% experience recurrency within one year. To improve outcomes in DFU care, activated autologous platelet-rich plasma (aaPRP) is one of the adjuvant therapies proposed. Containing various bioactive proteins such as growth factors and cytokines, it possesses regenerative, antioxidative, anti-inflammatory, and antimicrobial qualities. Furthermore, its autologous nature, which also makes it a highly safe treatment modality, is also promising. In this review, we shortly discuss the pathogenesis of DFUs and how aaPRP may tackle the key players in DFU pathogenesis to improve wound healing outcomes. We also briefly describe its method of isolation and the current views on aaPRP from an authoritative source. Lastly, we summarize the existing evidence for the utilization of aaPRP in the treatment of DFUs.

Assessment of metal-reducing bacteria residing in industrial wastewater: a bacterial-based bioremediation approach

Summary: Metals are required in minor amounts in the human body to perform vital functions, but beyond that level, they become toxic and cause many harmful effects. At present, polluted water is a large source of these heavy metals inside our body. Bioremediation is one of best treatments for the removal of these heavy metals from water. Objectives: The main objective of the current study was to isolate metal-reducing bacteria from soil and wastewater samples from different industries. Furthermore, the metal reducing potential of the bacteria was also evaluated under various environmental conditions (pH, temperature, incubation time, and UV exposure).

Toward a Diagnostic Test for Human African Trypanosomaisis

Summary: Human African Trypanosomiasis (HAT), caused by Trypanosoma brucei, T. brucei, disproportionately affects inhabitants of Sub Saharan Africa. T. brucei gambiense and T. brucei rhodesiense are the only strains that produce illness in humans. The purpose of this project is to determine if T. brucei Superoxide Dismutases, TbSODs, can be used as a biomarker for positive diagnosis of HAT. The hypothesis to be tested is if a rat is infected with T. brucei, then it will have traces of tbSOD in its bloodstream because as the rat’s immune system fights T. brucei infection some parasitic cells will lyse excreting many internal proteins including SOD into the bloodstream. Our methodology will consist of developing a modified version of the Villagran et al 2005 protocol whereby a series of blood tests will be performed on infected rats. If the blood tests positive for TbSOD then it is assumed that they have a strain of T. brucei. Finally, after confirming the presence of TbSOD, we will use ELISA to establish a correlation between TbSOD’s level and the degree of progression of the infection.

Antibacterial Activity of Bio Synthetic Silver Nanoparticles Against Escherichia Coli And Salmonella Typhimurium Using Moringa Oleifera Leaves Extract

Summary: Objectives: Antibacterial activity of bio synthetic silver nanoparticles against Escherichia coli (E. coli) ATCC 8739 and Salmonella typhimurium (S.typhi) ATCC 14028 using Moringa oleifera leaves extract was investigated. Materials and Methods: Prepared silver nanoparticles were characterized by using different techniques included: Ultraviolet Visible Spectroscopy (UV-VIS spectra analysis), Fourier transform infrared spectroscopy (FTIR) and Transmission electron microscope (TEM). The comparison between the antibacterial activities of the concentration 100 µg/ml of bio synthetic silver nanoparticles using Moringa oleifera leaves extract and 100 µg/ml of silver nitrate solution tested against E. coli reference strain ATCC 8739 and S. typhi ATCC 14028 was evaluated by using agar diffusion assay method. Results: FTIR analysis was showed the reduction action of Moringa oleifera leaves extract to form Silver Nanoparticles. TEM shows a dispersion of nanoparticles in a range (15.22 nm – 29.45) by using Moringa oleifera leaves extract. The antimicrobial activity of the concentration 100 µg/ml of synthetized silver nanoparticles was approved against E. coli reference strain ATCC 8739 by showing zone of inhibition against E. coli equal to 18 mm, while 100 µg/ml of the silver nitrate solution showed zone of inhibition against E. coli equal to 17 mm. While The antimicrobial activity of the concentration 100 µg/ml of synthetized silver nanoparticles which tested against S.ty phi reference strain ATCC 14028 by showing showed zone of inhibition against equal to 21 mm, while 100 µg/ml of the silver nitrate solution showed zone of inhibition against S.typhi equal to 15mm

In Vitro Propagation of Zingiber Officinale Rosc

Summary: Ginger (Zingiber officinale Rosc.) has become more popular in recent years because of its low toxicity and its broad spectrum of biological and pharmacological applications. These applications include antitumor, antioxidant, anti-inflammatory, antiapototic, cytotoxic, antidiabetic, anti-proliferative and anti-platelet activities. Traditionally, ginger can be propagated by using the fingers of the ginger rhizomes however early in the crop, disease can cause severe losses. Ginger propagation is usually performed with rhizome which depends on the availability of good quality seed rhizome. Alternatively, tissue culture technology can be used for the propagation of ginger. Tissue culture ginger has been considered vital for germplasm conservation and the resuscitation of the ginger industry in Jamaica in response to the ginger rhizome rot disease. Research from trials (unpublished) performed at the Scientific Research Council (SRC), Jamaica, indicated that the yellow variety of the Jamaican ginger have a lower multiplication rate than the Jamaican blue variety. Micropropagation of the Jamaica yellow explants was done on three growth media types. Explants were cut to approximately 1cm in height and transferred to media (S, F, M). The shoots developed in vitro were separated and subcultured on same medium for multiplication and rooting over a 6-week period. Growth parameters were evaluated during the course of the study. These included number of shoots, height of shoot and number of leaves. This study aims to investigate the performance of Jamaica’s yellow ginger variety on different nutrient media. Media M appears to be the most effective for the growth and multiplication of Jamaican yellow ginger variety when compared to Media S and F. However, there remains a need for further research in improving media M to obtain optimal growth of ginger explants in vitro.

Approaches from Resveratrol Activities on Central Nervous System Inflammation

Summary: Neuroinflammation is a common protective mechanism in homeostasis breakdown processes on the central nervous system. The prolongation of this process is responsible for the primary immune response of many neurodegenerative diseases. Understand these mechanisms has brought more effective alternatives to the scientific literature, on development of more effective pharmacological interventions. However, allopathic means of intervention to inflammation are sometimes insufficient to promote a good prognosis and reversal of the inflammatory process. Resveratrol is a polyphenol from the stilbene class, that has shown anti-inflammatory characteristics in several disease study methods, mainly in the ability to generate neuroprotection in neuroinflammatory damage models, reducing the production of pro-inflammatory cytokines and allowing survival, as well. Neuronal regeneration activity also as saw mainly through neurotrophin modulation and antioxidant activity. Resveratrol has shown promise in reversing neuronal death, an important activity in the face of the special needs for new drugs, capable enough to promoting better survival for patients with neurodegenerative diseases. In this review, it’s possible saw that Resveratrol has significant characteristics for future use in the treatment of neurodegenerative diseases.

Detection of Sole and Clonal Aneuploidy in Hematologic Malignant Diseases

Summary: Numerical chromosomal aneuploidy has diagnostic and prognostic value in detection of cancer. Hence, the study was undertaken in leukemic cases in our diagnostic laboratory. Analysis of 211 leukemic blood samples from referral cases of Neuberg Supratech Referral Laboratory (NSRL), Ahmedabad, India, since 2017 to 2019 using WHO protocols for chromosomal study. Detection of 23 cases were obtained (23/ 211: 11%) with this condition. Trisomy 8, 11, 13, 21 and monosomy 7 contributed to 18 cases (18/ 23; 78%) with 5 clonal anomaly (5/23; 22%). Four clonal patients were +8, +21 and +21, XXY and -7 with XY cells. Another karyotype with 48,XY,+8,+19/ 47,XY,+8 was detected which seems to be a new cytogenetic anomaly in the literature causing haematologic neoplasms in this cohort.

A Multi-Level Layout Algorithm for Identifying Highly Interacted Human Protein Complexes and Various Protein Pathways

Summary: Discovering highly interacting proteins and its pathways is a challenge for computational biologists. Identifying interactions among proteins and its pathways has been found to be useful for drug development. In our study, we collected data of 40,788 protein - protein interactions from HPRD and IntAct. This pooled off data was loaded into cytoscape (version 2.63) to visualize the human interactome network through the grid layout method. By using Connected Component (CC) algorithm, the largest and the highly connected human network were found. From 36,945 binary protein – protein interactions, 89 highly connected modules were selected, which are of high score value. The total numbers of proteins in each of the 89 modules were found out. The proteins from all the 89 clusters were classified into 2 categories - normal and diseased pathways. From all these 89 clusters, 1350 proteins were obtained and were unique, of which 374 proteins are in the normal pathways and 976 proteins in diseased pathways. But 976 proteins were found in both normal and diseased pathways. Further computational studies can help to understand the changes that occur in the proteins to become in the diseased pathways.

Phytochemical and Anti-nutritional potentials of leaves and stem-bark of Cathormion altissimum (Hook.f.) Hutch. & Dandy

Summary: The phytochemical and anti-nutritional constituents of leaves and stem-bark of Cathormion altissimum (Hook.f.) Hutch & Dandy was evaluated. The leaves and stem-bark of Cathormion altissimum used for this study were obtained from several communities in the eight local government area of Bayelsa State, Nigeria. The plant was qualitatively and quantitatively analyzed for some phytochemical and anti-nutrients constituents. The results of quantitative analysis showed that alkaloids, saponins, flavonoids, glycosides, phytate, tannins, oxalate and phenols concentrations were 8.04%, 7.7%, 6.94%, 0.432mg/kg, 0.0917%, 2.684%, 71.0 mg/g and 1002.88 mg/kg, respectively in the leaves, and 3.36%, 5.0%, 3.36%, 0.432mg/kg, 0.0917%, 1.026%, 18.10 mg/g and 62.88 mg/kg, respectively in the stem-bark. The qualitative results showed that saponins in both plant parts was very highly present, flavonoids in leaf and tannins in stem-bark were highly present, while terpenes, steroids, phenol in both plant parts and flavonoids in stem-bark and tannins in leaf were fairly present. The study showed that the leaf and stem-bark of the plant has pharmacological potentials against different diseases. While the phytate and oxalate suggests that the plant could be toxic over a prolonged period of use. As such, there is the need for research to be carried out to evaluate the concentration of the anti-nutrients that could be toxic to humans, and therapeutic properties of both plant parts.

Detection of Hemolytic Activity of Aeromonas sp Isolated from Water Samples of Coastal Area, Kochi

Summary: Aeromonas is a Gram negative rod shaped bacteria that causes gastroenteritis, wound infections and sometimes respiratory diseases. They are frequently isolated from fishes and from water. The aim of this study is to isolate and identify Aeromonas sp from different water samples in and around Kochi. Out 16 different water samples collected of which 7 showed positive for presence of Aeromonas sp. Starch ampicillin agar was used for Aeromonas isolation and the colonies were identified phenotypically and genotypically through biochemical characterization and 16S rRNA amplification respectively. Further hemolytic activity of Aeromonas sp isolates were performed on 5% blood agar plates in which 3 samples showed hemolytic activity. The hyl gene responsible for hemolysis in Aeromonas sp were detected using PCR. These findings show that the Aeromoas sp species isolated from water samples are enterotoxigenic.

Isolation and Identification of a Fungus Infecting Egyptian wheat grains Gamiza11 Triticum aestivum

Summary: The Penicillium species are among the most commonly occurring and economically important members of micro-fungi family. In this study, Molecular identification of fungal isolates were used to group and determine genetic variability of Penicillium isolate from Egyptian Gamiza11 wheat grains Triticum aestivum were obtained from Agricultural Administration in Menouf, Governorate of Menoufia, Egypt. The fungal DNA was then sent to SolGent Company, Daejeon South Korea for polymerase chain reaction (PCR) and gene sequencing. PCR was performed using two universal fungal primers ITS1 (forward) and ITS4 (reverse) which were incorporated in the reaction mixture. Molecular analysis also indicated genotype variability between the isolates with little correlation with either the origin of soil or geographical location.

Heavy Metal Assessment of Unripe Plantain Flour Sold in Some Markets in Osun State, Nigeria

Summary: Heavy metals, such as cadmium, arsenic and lead, are important environmental pollutants, particularly in areas with high anthropogenic pressure. Their presence in the atmosphere, soil and water, even in traces can cause serious problems to all organisms, and heavy metal bioaccumulation in the food chain especially can be highly dangerous to human health. Heavy metals enter the human body mainly through two routes namely: inhalation and ingestion, ingestion being the main route of exposure to these elements in human population. Heavy metals intake by human populations through food chain has been reported in many countries. This research work evaluated the level of heavy metals in plantain flour displayed in open containers for sale in ten locations alongside two packaged brands in Osun State. Heavy metals in the 12 samples were determined using Atomic Absorption Spectrophotometer (AAS).The average concentration for each heavy metal in all the samples ranged between 0 – 120.23 mg/kg for arsenic, 0.50 – 4.51 mg/kg for cadmium and lead was not detected in any of the samples. These findings indicate that foods displayed in open containers in markets or road sides are contaminated by the polluted environments. Excessive consumption can increase the level of heavy metal contamination in the body which may affect the health of the consumers.

Recovery of Agro-based Bio-Products from Cattle Farm Waste Using Aerobic Fluidized Crystallization Reactor

Summary: Plenty of well proven anaerobic methods are in existence to leisurely convert cattle farm waste into useful derivatives such as manure. But, unfortunately, anoxic processes are hectic and quite hard to comply with. Thus, the present study aimed to primarily address highend solutions to overcome the technical drawbacks of the existing anaerobic methods. Nutrients from the cattle farm waste streams were recovered by aerobic treatment mechanism, utilizing fluidized bed reactor (FBR) with dairy and goat manures as feed influents. In order to optimize the recovery, an effective pH value was determined and upheld by using a buffer solution of MgCl2.6H2O and NaOH. The maximum amount of struvites recovered from goat wastes was 93.2% of magnesium, 70.2% of ammonia, and 92.2% of phosphate. While the witnessed recovered fractions were scanty in the case of dairy wastes, which were as follows: 92.2% of magnesium, 68.2% of ammonia, and 91.2% of phosphate. The influence of pH and HRT on the yield of nutrient recovery has played a significant role. The study revealed supplementary recovery was achieved at the optimum condition (i.e., pH 9.0, HRT 2h) when the influent stream was doused with 0.06 M Mg2+. Ultimately, it was concluded that goat manure has a higher capacity of removing the nutrients compared to the dairy manure.

Editors-in-Chief

Call for editors of biotechnological research.

Biotechnological Research seeks applications from enthusiastic researchers and scholars who can oversee and maintain the editorial direction of the journal to ensure a steady flow of engaging and thought-provoking original research publications.

Journal Information

ISSN : 2395-6763 DOI Prefix : 10.15419 Indexed : Google Scholar

Alireza Heidari , California South University (CSU), Irvine, California, USA Phuc Van Pham , Vietnam National University Ho Chi Minh City, Viet Nam

Editorial Board 

Support Team : [email protected]; [email protected] Managing Editor : [email protected]

Annual Journal Metrics

Speed 21 days to first decision for all manuscripts 35 days from submission to acceptance 9 days from acceptance to publication

Journal Citation Indicator (JCI) Not yet

Journal Impact Factor (JIF) Not yet

Acceptance Rate 67.02%

Subscribe to receive latest news and articles

If you would like to automatically receive newletters and alerts from Biomedpress, please fill the form .

Tweets by biomed_press

IMAGES

  1. Research paper on biotechnology pdf

    biotechnological research papers

  2. (PDF) Application of biotechnology in sericulture: Progress, scope and

    biotechnological research papers

  3. (PDF) RESEARCH PAPER Biotechnological production of 1,3-propanediol

    biotechnological research papers

  4. 😎 Research papers on biotechnology. Research papers, journal articles

    biotechnological research papers

  5. (PDF) Status of Biotechnological Processes in the Pharmaceutical Industry

    biotechnological research papers

  6. Research papers in biotechnology free

    biotechnological research papers

VIDEO

  1. Biotechnological applications in Agriculture-Biology-Session 196

  2. LM6

  3. PlasmidFactory Corporate Video_english 1080p HD

  4. 🧬🔬Introducing Biotechnological Services at SLIBTEC🧪

  5. Biotechnological Application In Agriculture l GMO

  6. ZEISS Lightsheet Z.1: Arabidopsis root growth

COMMENTS

  1. Biotechnology

    Biotechnology articles from across Nature Portfolio. Atom. RSS Feed. Biotechnology is a broad discipline in which biological processes, organisms, cells or cellular components are exploited to ...

  2. Current Research in Biotechnology

    Current Research in Biotechnology (CRBIOT) is a new primary research, gold open access journal from Elsevier.CRBIOT publishes original papers, reviews, and short communications (including viewpoints and perspectives) resulting from research in biotechnology and biotech-associated disciplines. Current Research in Biotechnology is a peer-reviewed gold open access (OA) journal and upon acceptance ...

  3. Current research in biotechnology: Exploring the biotech forefront

    Starting in the mid-1980s, biotechnology became a very popular word in the title of research publications, appearing in papers concerning business, industry, biomedicine, chemical engineering, agricultural sciences, and even social sciences (Kennedy, 1991). In short, biotechnology signifies a new biological approach to a wide range of industries.

  4. Research articles

    Read the latest Research articles from Nature Biotechnology. ... Research Note (8) Research Paper (510) Resource (72) Roundtable (3) Speakers (61) Technical Report (92) Technologies (11)

  5. Plant biotechnology

    Haploids fast-track hybrid plant breeding. Two studies report the use of paternal haploids to enable one-step transfer of cytoplasmic male sterility in maize and broccoli, which resolves a key ...

  6. Human Molecular Genetics and Genomics

    Genomic research has evolved from seeking to understand the fundamentals of the human genetic code to examining the ways in which this code varies among people, and then applying this knowledge to ...

  7. Biotechnology Advances

    Research Reviews Biotechnology Advances is a review journal which considers all aspects of the multidisciplinary field. The scope includes biotechnology principles and applications in industry, agriculture, medicine, environmental concerns and regulatory issues. Authoritative articles on current de…. View full aims & scope $5300

  8. National Center for Biotechnology Information

    GenBank release 260.0 (4/19/2024) is now available on the NCBI FTP site. This release has 31.18 trillion bases and 4.46 billion records. The current release has: 250,803,006 traditional records containing 3,213,818,003,787 base pairs of sequence data 3,333,621,823 WGS records containing 27,225,116,587,937 base pairs of sequence data 741,066,498 ...

  9. An Introduction to Biotechnology

    The biotechnological tools are employed toward modification of the gene for gain of function or loss of function of the protein. The technique of removing, adding, or modifying genes in the genome or chromosomes of an organism to bring about the changes in the protein information is called genetic engineering or recombinant DNA technology (Fig ...

  10. Home

    Research Paper 24 April 2024 Cell line-specific impact of dexamethasone on the bioprocessing of Chinese hamster ovary cells. Yeong Bin An; Da Eun Kang; Jong Kwang Hong; Research Paper 23 April 2024 Study on the S239D/I332E mutation effect on the kinetics of Fc-Fc receptor binding through transition complex theory ...

  11. A brief overview of global biotechnology

    Between 2016 and 2019, the number of businesses involved in biotechnological research increased. In 2019, 1692 people worked in biotechnology activities and the total R&D expenditure in these activities was approximately 325 million TL in the same year. ... A Briefings Paper with Six Proposals Commissioned by UNIDO. 2002; ISSN:1534-6447. Vol ...

  12. Environmental biotechnology

    Environmental biotechnology articles from across Nature Portfolio. Atom; RSS Feed; Definition. Environmental biotechnology is the branch of biotechnology that addresses environmental problems ...

  13. Biotechnology Reports

    Biological and Biotechnological Applications of Natural Bioactives and Biochemicals. Edited by Vijai K. Gupta. 25 July 2022. View all special issues and article collections. View all issues. Read the latest articles of Biotechnology Reports at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.

  14. Emerging biotechnology applications in natural product and synthetic

    The number of papers published in the last 15 years (2007-2022) included in the Web of Science was searched with the keywords "pharmaceutical analysis" combined with "chemical analysis" or "biological analysis". ... Although biotechnological approaches cannot provide chemical information ... This research provides ideas for ...

  15. 362021 PDFs

    Biotechnology | Explore the latest full-text research PDFs, articles, conference papers, preprints and more on BIOTECHNOLOGY. Find methods information, sources, references or conduct a literature ...

  16. Biomedical and Biotechnology Research Journal (BBRJ)

    Distinct Host Gene Targets and Mode of Action in the MicroRNA of Nipah Virus from Malaysia and Bangladesh: A Comparative in-silico Based Analysis. Dsouza, Norine; Gupta, Deepti Bhushan; Chellasamy, Selvaa Kumar. Biomedical and Biotechnology Research Journal. 7 (3):340-350, Jul-Sep 2023. Abstract.

  17. (PDF) Biotechnology

    This paper aims to identify and analyse the key elements that can guarantee a successful project in a biotechnological field, using both the theoretical approach and the author's own expertise in ...

  18. Animal biotechnology

    Animal biotechnology is a branch of biotechnology in which molecular biology techniques are used to genetically engineer (i.e. modify the genome of) animals in order to improve their suitability ...

  19. Biotechnology Research and Innovation

    Strategies for crop improvement under biotic and abiotic stresses. Edited by Alessandra Alves de Souza, Paulo Cavalcanti Gomes Ferreira, Robert Miller. 2019. Read the latest articles of Biotechnology Research and Innovation at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.

  20. Plastic-Eating Microorganisms: Recent Biotechnological Techniques for

    Biotechnological techniques used for the biodegradation of plastics ... 14 research papers, 5 books and 16 book chapters with Springer, 1 practical manual, 33 popular articles, and 2 editorials. ...

  21. Curcumin for Food and Biotechnological Applications

    Curcumin, a yellow polyphenolic pigment from the Curcuma longa L. (turmeric) rhizome, has been used for centuries for culinary and food coloring purposes, and as an ingredient for various medicinal preparations, widely used in Ayurveda and Chinese medicine. In recent decades, their biological activities have been extensively studied. Thus, this review aims to offer an in-depth discussion of ...

  22. Ethical principles for the use of human cellular biotechnologies

    The challenges related to biotechnologies have spawned conferences, white papers, and sets of guidelines, all trying to suggest ways to responsibly contain the power of biotechnologies, such as ...

  23. Biotechnological Research

    Biotechnological Research (ISSN 2395-6763) is an open access international peer reviewed journal. The Journal publishes quarterly (4 times an year) innovative research findings from applied biology fields. Main areas journal focuses: (1) Classical Biotechnology which includes the production of animal, plant and microbial bio-products, production optimization and their applications; (2 ...